San Francisco vs Buffalo NFL Props & Picks on James Cook

(Photo by Getty Images) James Cook

San Francisco (5-6-0) at Buffalo (9-2-0)

• When: Dec 1 2024, 8:20 PM
• Where: Highmark Stadium, Orchard Park, NY
• Where to watch: NBC

Game Odds, Spread, Moneyline & Total

San Francisco 49ers @ Buffalo Bills
Moneyline
San Francisco 49ers   +255
Buffalo Bills   -310

San Francisco 49ers @ Buffalo Bills
Point Spread
San Francisco 49ers   6.5 (EVEN)
Buffalo Bills   -6.5 (-120)

San Francisco 49ers @ Buffalo Bills
Total
Over   45.0 (-110)
Under   45.0 (-110)

• Odds source: Bovada Sportsbook
• Get real-time live scores & latest betting odds here!

James Cook Props Bets

San Francisco 49ers @ Buffalo Bills
Anytime Touchdown Scorer
James Cook (BUF)   -115

San Francisco 49ers @ Buffalo Bills
Alternate Rushing Yards – James Cook (BUF)
To Record 25+ Rushing Yards   -1400
To Record 40+ Rushing Yards   -400
To Record 50+ Rushing Yards   -225
To Record 60+ Rushing Yards   -145
To Record 70+ Rushing Yards   +110
To Record 80+ Rushing Yards   +160
To Record 90+ Rushing Yards   +225
To Record 100+ Rushing Yards   +325
To Record 110+ Rushing Yards   +450
To Record 125+ Rushing Yards   +750
To Record 150+ Rushing Yards   +1400

San Francisco 49ers @ Buffalo Bills
Total Rushing & Receiving Yards – James Cook (BUF)
Over   84.5 (-115)
Under   84.5 (-115)

San Francisco 49ers @ Buffalo Bills
Total Rush Attempts – James Cook (BUF)
Over   15.5 (-110)
Under   15.5 (-120)

San Francisco 49ers @ Buffalo Bills
Longest Rushing Attempt – James Cook (BUF)
Over   14.5 (-120)
Under   14.5 (-110)

San Francisco 49ers @ Buffalo Bills
Total Receiving Yards – James Cook (BUF)
Over   16.5 (-120)
Under   16.5 (-110)

San Francisco 49ers @ Buffalo Bills
Total Receptions – James Cook (BUF)
Over   2.5 (+130)
Under   2.5 (-170)

San Francisco 49ers @ Buffalo Bills
Alternate Receptions – James Cook (BUF)
To Record 1+ Receptions   -1400
To Record 2+ Receptions   -275
To Record 3+ Receptions   +105
To Record 4+ Receptions   +225
To Record 5+ Receptions   +400
To Record 6+ Receptions   +700

San Francisco 49ers @ Buffalo Bills
Longest Reception – James Cook (BUF)
Over   11.5 (-110)
Under   11.5 (-120)

James Cook Statistics

Game	Rushing Att	Catches	Total Yards	Total TDs
10	137	25	778	11

James Cook Past Results

W	vs	Score	Yds	Att	Y/A	Lg	TD
11	KC	W 30-21	20	9	2.2	6	2
10	@ IND	W 30-20	80	19	4.2	20	1
9	MIA	W 30-27	44	10	4.4	13	0
8	@ SEA	W 31-10	111	17	6.5	18	2
7	TEN	W 34-10	32	12	2.7	11	1
6	@ NYJ	W 23-20	–	–	–	–	–
5	@ HOU	L 20-23	82	20	4.1	12	1
4	@ BAL	L 10-35	39	9	4.3	8	0
3	JAC	W 47-10	39	11	3.5	13	1
2	@ MIA	W 31-10	78	11	7.1	49	2
1	ARI	W 34-28	71	19	3.7	15	0

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NFL Player Props Picks & Predictions

James Cook Props Pick: Total Rushing & Receiving Yards – Under 84.5 (-115)
A $115 Bet on that Props will return $215

• NFL Props source: Bovada Sportsbook