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Oklahoma State (1-0) at Oregon (1-0)
- When: Sep 6 2025, 3:30 PM
- Where: Autzen Stadium, Eugene, OR
- Where to watch: CBS
- Last Meeting: Oregon 42-31, December 20th, 2008
Oklahoma State vs (6) Oregon Preview & Prediction
Spread: Oregon -28.0
Moneyline: Oregon -7660
Total: 55.5
Oregon Ducks Betting Outlook
The Ducks opened their season by doing exactly what a top-10 team is supposed to do, flatten an FCS opponent. Oregon dismantled Montana State 59-13, scoring on every drive except the final kneel-down. That kind of ruthless efficiency is why they vaulted to No. 6 in the AP Poll.
Quarterback Dante Moore was sharp and composed, completing 18 of 23 passes for 213 yards and three touchdowns. For a player whose UCLA days ended with question marks, this was a statement outing. Oregon’s ground attack pitched in with five touchdowns, showing their offensive balance is alive and well.
Defensively, the Ducks smothered a Montana State team that led all of college football in rushing yards last season. Holding them to just 46 rushing yards was no small feat. With key contributors like Theran Johnson and Emmanuel Pregnon expected back this week, the defense could be even stingier.
Against an Oklahoma State squad that’s already shorthanded, Oregon looks primed to flex again.
Oklahoma State Cowboys Betting Outlook
The Cowboys come in with more problems than points. They took care of UT Martin 27-7 in Week 1, but it came at a cost. Starting quarterback Hauss Hejny broke his foot in the first quarter, leaving third-year passer Zane Flores to run the show. Flores was serviceable in relief, going 13-of-20 for 136 yards, but now faces a whole different level of opponent in Oregon.
Defensively, Oklahoma State had a bright spot in linebacker Wendell Gregory, who recorded three sacks in one half before legal issues off the field made headlines. Despite his arrest, head coach Mike Gundy says Gregory will play. Even so, the Cowboys are also dealing with injuries to center Kasen Carpenter and defensive end DeSean Brown.
The offense leans on Flores’ ability to manage the game, but against Oregon’s aggressive defense, keeping pace will be a steep climb.
Prediction & Betting Angle
Oregon has the better quarterback, the deeper roster, and the healthier team. The Ducks should control the tempo early and force Oklahoma State into catch-up mode, which doesn’t bode well with Flores making his first start. The Ducks’ offense is explosive enough to push this one into the high 50s by themselves.
Final Score: Oregon 45, Oklahoma State 13
Lean: Oregon -28.0
Total: Over 55.5
- NCAA Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
