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Kansas City (0-2-0) at NY Giants (0-2-0)
- When: Sep 21 2025, 8:20 PM
- Where: MetLife Stadium, East Rutherford, NJ
- Where to watch: NBC
- Last Meeting: KC 20-17, November 1st, 2021
Kansas City vs NY Giants Preview & Prediction
Spread: Kansas City -6.5
Moneyline: Kansas City (-330)
Total: 44.5
Kansas City Chiefs: Searching for That First Win
Patrick Mahomes and the Chiefs don’t usually stumble into 0-2 starts. In fact, it hasn’t happened since Andy Reid’s early days in 2014. Now, Kansas City enters Week 3 with urgency, desperate to avoid an 0-3 hole few teams recover from.
The Chiefs’ offense hasn’t been its usual high-powered self. Mahomes leads the team in rushing but has been bottled up as a passer, completing just 40 of 68 throws with two touchdowns. With Rashee Rice suspended and Xavier Worthy only recently back in practice, Mahomes is dealing with a reshuffled receiving corps.
Even so, Mybookie oddsmakers still have Kansas City as a 6.5-point road favorite. The motivation factor looms large here: the Chiefs cannot afford to slip further in the standings, and bettors know urgency often translates to sharper execution.
Prop Pick – Patrick Mahomes to Throw 2+ Passing TDs – When the pressure rises, Mahomes usually delivers. With weapons trending back toward full health, two scores feels well within reach.
New York Giants: Heavy Underdogs, But Fighting Spirit
The Giants also enter at 0-2, but their offense finally showed life in last week’s shootout loss at Dallas. Russell Wilson carved the Cowboys’ secondary for 450 yards and three touchdowns, though his overtime interception proved costly.
Receiver Wan’Dale Robinson was a bright spot, posting eight catches for a career-best 142 yards. That confidence could carry into this matchup, especially with left tackle Andrew Thomas potentially making his long-awaited return. His presence would stabilize an offensive line that has struggled for consistency.
The Giants’ challenge: stop Mahomes in a spot where he’s rarely rattled. While their defense is tough at times, they’ll need to limit big plays and stay disciplined to keep this within reach.
Prop Pick – Wan’Dale Robinson Over 43.5 Receiving Yards – Robinson’s chemistry with his QB looks strong, and he’s the most reliable chain-mover in this offense right now.
NFL Expert Prediction
Kansas City has history, pride, and urgency on its side, while the Giants are still piecing things together. Look for Mahomes to finally settle in and the Chiefs’ defense to clamp down in key moments.
Final Score: Chiefs 27, Giants 20
Lean: Kansas City -6.5
Total: Over 44.5
- NFL Football Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
