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Mets vs Pirates Opening Day Picks & Prediction

New season begins with Mets vs Pirates betting preview.

(Photo by Getty Images) Freddy Peralta
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Pittsburgh (0-0) at NY Mets (0-0)

  • When: Mar 26 2026, 1:15 PM
  • Where: Citi Field, Flushing, Queens
  • Where to watch: NBC/Peacock

Pittsburgh vs NY Mets MLB Preview & Pick

Moneyline: NY Mets -116 
Runline: NY Mets -1.5 (+180)
Total: 7.0

New York Mets Betting Breakdown

New look Mets, new expectations. After falling short last season, New York hit reset and brought in serious upgrades, starting with Freddy Peralta. The right-hander arrives after a dominant 17-6 season with a 2.70 ERA and has historically handled Pittsburgh well, posting a 3.36 ERA across multiple matchups.

This lineup has a completely different feel. Marcus Semien adds stability, Bo Bichette shifts the infield dynamic, and Luis Robert Jr. brings upside if he stays healthy. The bullpen also gets a major boost with Devin Williams anchoring late innings.

From a betting standpoint, the Mets at -116 reflect both roster upgrades and pitching confidence. At home, with a deeper lineup and a proven arm on the mound, they hold a slight edge.

Pittsburgh Pirates Betting Breakdown

Pittsburgh is no longer the same low-scoring group from last season. After finishing near the bottom in runs, they made aggressive moves to fix the offense. Brandon Lowe, Ryan O’Hearn, and Marcell Ozuna all bring power, and if Bryan Reynolds rebounds, this lineup becomes far more dangerous.

Of course, everything starts with Paul Skenes. The reigning Cy Young winner posted a 1.97 ERA and has already shown he can dominate elite lineups. He gives Pittsburgh a chance every time he takes the ball.

Still, there are questions. Oneil Cruz has elite speed with 38 stolen bases, but his .200 average highlights ongoing inconsistency. This offense has upside, but it needs to prove it can deliver consistently against quality pitching.

MLB Betting Prediction

This is a tight line for a reason. Mets at -116 and a total of 7.0 signals a classic pitcher’s duel between Peralta and Skenes.

Both arms can control this game early, which leans toward a lower-scoring environment. However, New York’s deeper lineup and home-field advantage provide a slight edge in a matchup that could come down to late innings.

Pittsburgh has the ace to steal it, but over nine innings, the Mets look better positioned to capitalize.

Final Score: Mets 3, Pirates 2
Lean: Mets Moneyline (-116)
Total: 
Under 7.0 

The Masters 2026 Odds

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