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Dodgers vs Dbacks Opening Day Picks & Odds

Opening Day Arizona and LA Dodgers odds, picks, preview.

(Photo by Getty Images) Yoshinobu Yamamoto
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Arizona (0-0) at LA Dodgers (0-0)

  • When: Mar 26 2026, 8:30 PM
  • Where: Dodger Stadium, Los Angeles
  • Where to watch: NBC/Peacock

Arizona vs LA Dodgers MLB Preview & Pick

Moneyline: LA Dodgers -265 
Runline: LA Dodgers -1.5 (-125)
Total: .0

Los Angeles Dodgers Betting Breakdown

The champs are back, and the market is pricing them exactly how you would expect. Los Angeles opens the season with Yoshinobu Yamamoto on the mound, and this is not just any starter. He posted a 2.49 ERA last season and dominated Arizona in past matchups with a 1.93 ERA. He also delivered on the biggest stage, earning World Series MVP honors with clutch outings.

This lineup is built to overwhelm. Shohei Ohtani sets the tone, Kyle Tucker adds depth, and Mookie Betts plus Freddie Freeman keep pressure on every inning. There are no breaks in this order. From a betting perspective, this is one of the most complete teams in baseball entering Opening Day.

Arizona Diamondbacks Betting Breakdown

Arizona walks into a brutal spot to start the season. Injuries are already stacking up, with Corbin Burnes and Merrill Kelly unavailable. That puts the pressure on Zac Gallen, who had a 4.83 ERA last season and has struggled against the Dodgers with a 2-5 record.

Corbin Carroll is back, but not at full form after limited production in spring action. The lineup still has experienced pieces like Ketel Marte and Nolan Arenado, but overall, this group looks thin compared to Los Angeles.

The biggest concern is depth. The bullpen is shorthanded, and facing a lineup like this early in the season is a tough assignment.

MLB Betting Prediction

The Dodgers are heavy favorites at -260, and that number reflects the clear gap between these teams. The spread at -1.5 (-125) is where the real value sits.

With Yamamoto controlling the game early and the Dodgers lineup capable of putting up runs in bunches, this sets up as a multi-run win scenario. Arizona’s pitching depth and current injuries make it difficult to see them keeping pace for nine innings.

The total at 9.0 indicates scoring potential, but the safer angle is backing Los Angeles to win comfortably.

Final Score: Dodgers 7, Diamondbacks 3
Lean:  LA Dodgers -1.5 (-125)
Total: 
Over 9.0 (+100) 

The Masters 2026 Odds

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