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Cleveland vs Detroit MLB Props & Picks on Riley Greene

The Guardians and Riley Greene’s Tigers will meet on the field at Comerica Park.

(Photo by Getty Images) Riley Greene
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Cleveland (29-22) at Detroit (20-30)

  • When: May 21 2026, 1:10 PM
  • Where: Comerica Park, Detroit
  • TV: CLEG

Game Odds, Runline, Moneyline & Total

Cleveland Guardians @ Detroit Tigers
Moneyline

Cleveland Guardians   -102
Detroit Tigers   -118

Cleveland Guardians @ Detroit Tigers
Runline

Cleveland Guardians   1.5 (-225)
Detroit Tigers   -1.5 (+185)

Cleveland Guardians @ Detroit Tigers
Total

Over   7.0 (-125)
Under   7.0 (+105)

Riley Greene MLB Preview & Props

Riley Greene has been one of the most dangerous bats in the Detroit Tigers lineup this season, consistently delivering hard contact and driving offensive production. His ability to hit for average while creating runs and RBI opportunities has made him a key centerpiece in Detroit’s offense, especially during high-pressure situations against quality pitching throughout the MLB season.

Cleveland Guardians @ Detroit Tigers
Player to hit a Home Run

Riley Greene (DET)   +700

Cleveland Guardians @ Detroit Tigers
Player to hit 2+ Home Runs

Riley Greene (DET)   +10000

Cleveland Guardians @ Detroit Tigers
Player to record a Hit

Riley Greene (DET)   -170

Cleveland Guardians @ Detroit Tigers
Player to record 2+ Hits

Riley Greene (DET)   +350

Cleveland Guardians @ Detroit Tigers
Player to record a Run

Riley Greene (DET)   +115

Cleveland Guardians @ Detroit Tigers
Player to record 2+ Runs

Riley Greene (DET)   +850

Cleveland Guardians @ Detroit Tigers
Player to record a RBI

Riley Greene (DET)   +185

Cleveland Guardians @ Detroit Tigers
Player to record 2+ RBIs

Riley Greene (DET)   +550

Cleveland Guardians @ Detroit Tigers
Total Hits, Runs and RBIs – Riley Greene (DET)

Over   1.5 (+110)
Under   1.5 (-145)

Cleveland Guardians @ Detroit Tigers
Player to record a Single

Riley Greene (DET)   +115

Cleveland Guardians @ Detroit Tigers
Total59 Doubles – Riley Greene (DET)

Over   0.5 (+400)
Under   0.5 (-650)

Cleveland Guardians @ Detroit Tigers
Player to record a Stolen Base

Riley Greene (DET)   +1500

Riley Greene Statistics

GP AVG Hits HR RBI Run SB TB
50 .333 59 4 24 29 1 86

Riley Greene Last 10

Date Opp Result AB R H 2B 3B HR RBI SO SB
May 20 vs CLE
L 3-2
4 0 1 0 0 0 0 2 0
May 19 vs CLE
L 4-3
2 2 2 0 0 0 0 0 0
May 18 vs CLE
L 8-2
2 0 2 1 0 0 1 0 0
May 17 vs TOR
L 4-1
4 0 0 0 0 0 0 2 0
May 16 vs TOR
L 2-1
4 0 1 0 0 0 0 2 0
May 15 vs TOR
W 3-2
4 0 1 1 0 0 1 2 0
May 14 @NYM
L 9-4
3 1 2 0 0 0 0 0 0
May 13 @NYM
L 3-2
5 0 3 0 0 0 2 0 0
May 12 @NYM
L 10-2
4 0 1 0 0 0 0 1 0
May 10 @KC
W 6-3
3 1 2 1 0 0 0 1 0

MLB Baseball Props Picks & Predictions

Riley Greene has been one of the hottest bats in the lineup this season, batting .333 with 59 hits while consistently driving in runs and creating scoring chances. His aggressive approach and ability to make quality contact should keep him heavily involved offensively against Joey Cantillo for the Detroit Tigers.

Riley Greene Props Pick: Total Hits, Runs and RBIs – Over 1.5 (+110)
A $100 Bet on that Props will return $210

MLB Odds & Props source: Bovada Sportsbook

U.S. Open 2026 Odds

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