- This page contains affiliate links. We may earn a commission at no extra cost to you.
Pittsburgh (25-24) at St. Louis (28-20)
- When: May 21 2026, 1:15 PM
- Where: Busch Stadium, St. Louis
- TV: CARD
Game Odds, Runline, Moneyline & Total
Pittsburgh Pirates @ St. Louis Cardinals
Moneyline
Pittsburgh Pirates -130
St. Louis Cardinals +108
Pittsburgh Pirates @ St. Louis Cardinals
Runline
Pittsburgh Pirates -1.5 (+135)
St. Louis Cardinals 1.5 (-160)
Pittsburgh Pirates @ St. Louis Cardinals
Total
Over 7.5 (-105)
Under 7.5 (-115)
- Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
Dustin May MLB Preview & Props
Dustin May has looked sharp on the mound this season, using heavy movement and strong command to keep hitters uncomfortable throughout games. His ability to generate weak contact while staying efficient with pitch counts has helped him consistently work deeper into outings, giving the St. Louis Cardinals a reliable presence in the rotation lately.
Pittsburgh Pirates @ St. Louis Cardinals
Will Dustin May Record a Win?
Yes +200
No -300
Pittsburgh Pirates @ St. Louis Cardinals
Total Strikeouts – Dustin May (STL)
Over 4.5 (-135)
Under 4.5 (+105)
Pittsburgh Pirates @ St. Louis Cardinals
Alternate Strikeouts – Dustin May (STL)
3+ Strikeouts -1200
4+ Strikeouts -360
6+ Strikeouts +150
7+ Strikeouts +350
8+ Strikeouts +700
Pittsburgh Pirates @ St. Louis Cardinals
Total Hits Allowed – Dustin May (STL)
Over 5.5 (EVEN)
Under 5.5 (-140)
Pittsburgh Pirates @ St. Louis Cardinals
Total Pitcher Walks – Dustin May (STL)
Over 2.5 (+150)
Under 2.5 (-200)
Pittsburgh Pirates @ St. Louis Cardinals
Total Pitcher Outs – Dustin May (STL)
Over 17.5 (-135)
Under 17.5 (-105)
Dustin May Statistics
| Game | WL | ERA | IP | WHIP | K | BB |
| 9 | 3-4 | 4.81 | 48.2 | 1.42 | 35 | 15 |
Dustin May Last 10
| Date | Opp | Result | IP | H | R | ER | HR | BB | SO |
| May 15 | vs KC | W 5-4 |
6.0 | 4 | 3 | 3 | 0 | 4 | 3 |
| May 9 | @SD | L 4-2 |
6.0 | 3 | 3 | 2 | 1 | 2 | 7 |
| May 3 | vs LAD | L 4-1 |
6.0 | 7 | 3 | 3 | 0 | 2 | 3 |
| Apr 27 | @PIT | W 4-2 |
6.0 | 7 | 2 | 2 | 0 | 2 | 2 |
| Apr 21 | @MIA | W 5-3 |
5.1 | 6 | 1 | 1 | 1 | 1 | 5 |
| Apr 15 | vs CLE | W 5-3 |
6.0 | 6 | 1 | 1 | 0 | 1 | 4 |
| Apr 10 | vs BOS | W 3-2 |
6.0 | 4 | 2 | 1 | 0 | 0 | 4 |
| Apr 4 | @DET | L 11-6 |
3.1 | 7 | 7 | 7 | 2 | 2 | 4 |
| Mar 29 | vs TB | L 11-7 |
4.0 | 10 | 6 | 6 | 0 | 1 | 3 |
| Sep 3 | vs CLE | L 8-1 |
3.0 | 3 | 1 | 1 | 0 | 2 | 1 |
- MLB Daily Specials odds & props
- Today’s player props picks
MLB Baseball Props Picks & Predictions
Dustin May has been working deep into games consistently, going over six innings in each of his last four starts. His ability to generate weak contact while staying efficient with pitch counts has helped him stay on the mound longer, and against the Pittsburgh Pirates, another lengthy outing looks possible for the St. Louis Cardinals.
Dustin May Props Pick: Total Pitcher Outs –
Over 17.5 (-135)
A $135 Bet on that Props will return $235
MLB Odds & Props source: Bovada Sportsbook