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Pittsburgh vs St. Louis MLB Props & Picks on Dustin May

The Pirates and Dustin May’s Cardinals will meet on the field at Busch Stadium.

(Photo by Getty Images) Dustin May
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Pittsburgh (25-24) at St. Louis (28-20)

  • When: May 21 2026, 1:15 PM
  • Where: Busch Stadium, St. Louis
  • TV: CARD

Game Odds, Runline, Moneyline & Total

Pittsburgh Pirates @ St. Louis Cardinals
Moneyline

Pittsburgh Pirates   -130
St. Louis Cardinals   +108

Pittsburgh Pirates @ St. Louis Cardinals
Runline

Pittsburgh Pirates   -1.5 (+135)
St. Louis Cardinals   1.5 (-160)

Pittsburgh Pirates @ St. Louis Cardinals
Total

Over   7.5 (-105)
Under   7.5 (-115)

Dustin May MLB Preview & Props

Dustin May has looked sharp on the mound this season, using heavy movement and strong command to keep hitters uncomfortable throughout games. His ability to generate weak contact while staying efficient with pitch counts has helped him consistently work deeper into outings, giving the St. Louis Cardinals a reliable presence in the rotation lately.

Pittsburgh Pirates @ St. Louis Cardinals
Will Dustin May Record a Win?

Yes   +200
No   -300

Pittsburgh Pirates @ St. Louis Cardinals
Total Strikeouts – Dustin May (STL)

Over   4.5 (-135)
Under   4.5 (+105)

Pittsburgh Pirates @ St. Louis Cardinals
Alternate Strikeouts – Dustin May (STL)

3+ Strikeouts   -1200
4+ Strikeouts   -360
6+ Strikeouts   +150
7+ Strikeouts   +350
8+ Strikeouts   +700

Pittsburgh Pirates @ St. Louis Cardinals
Total Hits Allowed – Dustin May (STL)

Over   5.5 (EVEN)
Under   5.5 (-140)

Pittsburgh Pirates @ St. Louis Cardinals
Total Pitcher Walks – Dustin May (STL)

Over   2.5 (+150)
Under   2.5 (-200)

Pittsburgh Pirates @ St. Louis Cardinals
Total Pitcher Outs – Dustin May (STL)

Over   17.5 (-135)
Under   17.5 (-105)

Dustin May Statistics

Game WL ERA IP WHIP K BB
9 3-4 4.81 48.2 1.42 35 15

Dustin May Last 10

Date Opp Result IP H R ER HR BB SO
May 15 vs KC
W 5-4
6.0 4 3 3 0 4 3
May 9 @SD
L 4-2
6.0 3 3 2 1 2 7
May 3 vs LAD
L 4-1
6.0 7 3 3 0 2 3
Apr 27 @PIT
W 4-2
6.0 7 2 2 0 2 2
Apr 21 @MIA
W 5-3
5.1 6 1 1 1 1 5
Apr 15 vs CLE
W 5-3
6.0 6 1 1 0 1 4
Apr 10 vs BOS
W 3-2
6.0 4 2 1 0 0 4
Apr 4 @DET
L 11-6
3.1 7 7 7 2 2 4
Mar 29 vs TB
L 11-7
4.0 10 6 6 0 1 3
Sep 3 vs CLE
L 8-1
3.0 3 1 1 0 2 1

MLB Baseball Props Picks & Predictions

Dustin May has been working deep into games consistently, going over six innings in each of his last four starts. His ability to generate weak contact while staying efficient with pitch counts has helped him stay on the mound longer, and against the Pittsburgh Pirates, another lengthy outing looks possible for the St. Louis Cardinals.

Dustin May Props Pick: Total Pitcher Outs – Over 17.5 (-135)
A $135 Bet on that Props will return $235

MLB Odds & Props source: Bovada Sportsbook

U.S. Open 2026 Odds

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