Cleveland (27-22) at Detroit (33-18)
- When: May 23 2025, 7:10 PM
- Where: Comerica Park, Detroit
- Where to watch: FDSDET
Guardians vs. Tigers Betting Preview & Prediction
Moneyline: Detroit -130
Total: 8.5
Detroit Tigers Betting Outlook
Detroit has found a winning formula every time rookie Jackson Jobe takes the mound and bettors are riding the wave. The Tigers are 8-0 in Jobe’s starts this season, and the 22-year-old right-hander (4-0, 4.12 ERA) is coming off a strong performance against Toronto, where he allowed just two runs over six-plus innings. Jobe continues to build confidence, and his ability to pitch deep into games has kept Detroit’s bullpen fresh.
Manager A.J. Hinch praised Jobe’s command and poise under pressure, and there’s no reason to expect a drop-off here. He’s already had a brief taste of Cleveland in last year’s playoffs, so familiarity could play in his favor.
After a 7-0 loss in the series opener, the Tigers will be eager to bounce back and keep their slim lead atop the AL Central. A return to form behind Jobe makes the -130 price on the Moneyline appealing.
Cleveland Guardians Betting Outlook
The Guardians will counter with Slade Cecconi (0-1, 5.40 ERA), who showed flashes of potential in his season debut. Returning from an oblique injury, Cecconi struck out eight over five-plus innings against the Reds with a diverse six-pitch arsenal. The Tigers will see him for the first time, which gives Cecconi a slight edge in the early innings. However, Detroit’s offense will eventually key in on his mix if he doesn’t execute consistently.
Cleveland took Game 1 of the series with a dominant shutout and continues to lean on a red-hot pitching staff that’s allowed two or fewer earned runs in 17 of the last 21 games. Offensively, Jose Ramirez is the clear catalyst riding a 15-game hitting streak while batting .390 with seven multi-hit efforts in that span.
Betting Analysis & Score Prediction
The Guardians are dangerous, but Jobe’s mojo at home combined with Detroit’s desire to rebound makes them a solid pick on the Moneyline. Expect the Tigers to capitalize late as Cleveland cools off.
Final Score Prediction: Tigers 5, Guardians 3
Best Bet: Detroit RL -1.5 (+160)
Total: Under 8.5 (-115)
- MLB Odds source: MyBookie Sportsbook
