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Cubs vs Brewers MLB Baseball Odds & Parlay Picks

Divisional bragging rights will be on the line when Chi. Cubs and Milwaukee meet at American Family Field.

(Photo by Getty Images) Freddy Peralta
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Chi. Cubs (62-45) at Milwaukee (64-43)

  • When: Jul 30 2025, 2:10 PM
  • Where: American Family Field, Milwaukee
  • Where to watch: FDSWI

Cubs vs. Brewers – Game Betting Preview & Prediction

Moneyline: Milwaukee -122 
Spread: Milwaukee -1.5 (+165)
Total: 7.5

Chicago Cubs Betting Preview

The Cubs find themselves in a tight spot, trailing Milwaukee by two games in the NL Central after dropping the first two contests of this series. Wednesday’s matinee becomes crucial if Chicago wants to avoid a sweep and reclaim momentum.

Shota Imanaga (7-4, 3.12 ERA) will look to bounce back after his worst outing of the season, a 12-5 loss to the White Sox, where he allowed seven runs and three long balls. Since returning from a hamstring strain, Imanaga is 4-2 in six starts, but Milwaukee has been a tough nut for him to crack. He’s 0-2 against the Brewers, surrendering nine runs over 10 innings.

The Cubs’ offense hasn’t kept pace with Milwaukee, scoring just seven total runs across the first two games. Ian Happ’s health is also a concern after he fouled a pitch off his shin Tuesday, leaving his availability in question.

Milwaukee Brewers Betting Preview

Milwaukee is riding high, winning the first two games of the series by a combined 17-7 margin. Freddy Peralta (12-4, 2.81 ERA) continues to be the Brewers’ ace, going 6-0 over his last seven starts. He’s been dominant against the Cubs this year, posting a 2.45 ERA across 11 innings.

Andrew Vaughn has been an absolute revelation since arriving from the White Sox. His grand slam on Tuesday capped a six-RBI night, and he’s now hitting .375 with five home runs and 21 RBIs in just 15 games with Milwaukee. The Brewers’ offense looks dangerous even if Jackson Chourio, who left Tuesday’s game with a hamstring issue, is unavailable.

Prediction

The Cubs desperately need Imanaga to deliver, but Milwaukee’s lineup is hot, and Peralta’s consistency gives them a clear edge. Expect a lower-scoring battle early, but the Brewers’ bullpen and offensive depth should make the difference.

Score Prediction: Brewers 5, Cubs 3
Pick: Milwaukee (-122)
Total: Over 7.5 (-103) 

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