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Cleveland (64-60) at Arizona (60-66)
- When: Aug 19 2025, 9:40 PM
- Where: Chase Field, Phoenix
- Where to watch: MLB Network
Guardians vs Diamondbacks – Game Preview, Prediction and Player Props
Moneyline: Arizona -114
Total: 8.5
RunLine: Arizona -1.5 (+180)
Arizona Diamondbacks Betting Outlook
The Diamondbacks hand the ball to Eduardo Rodriguez (5-7, 5.40 ERA), who has absolutely owned Cleveland throughout his career. The lefty is a perfect 7-0 with a 2.51 ERA in nine starts against the Guardians, consistently keeping their bats quiet. Coming off his best outing of the season, seven sharp innings against Colorado, Rodriguez finally looks dialed in.
Offensively, Arizona needs to snap out of a funk after dropping four straight games. Their lineup has the pop to break out at any moment, especially in hitter-friendly Chase Field. With Rodriguez’s history of success against Cleveland, the D-Backs should feel confident about halting their skid.
Player Prop to Watch (Diamondbacks): Ketel Marte Over 1.5 Total Bases – He’s been the most reliable bat for Arizona and matches up well against Bibee.
Cleveland Guardians Betting Outlook
The Guardians counter with Tanner Bibee (9-9, 4.54 ERA), who has been unpredictable since July. He’s managed to win five of his last six decisions, but his 6.00 ERA in that stretch shows how much he’s leaned on run support rather than dominance.
C.J. Kayfus and Brayan Rocchio powered Cleveland in the series opener, and with the Guardians chasing a wild-card spot, every win is critical. The question is whether Bibee can avoid the big inning against a team he beat last season at Chase Field.
Player Prop to Watch (Guardians): José Ramírez to Record an RBI – He’s the Guardians’ best clutch hitter and the one most likely to crack Rodriguez’s streak.
MLB Prediction & Betting Angle
This matchup sets up as a tight one. Rodriguez’s track record vs. Cleveland gives Arizona the edge, but the Guardians’ lineup has been scrappy enough to keep them alive.
Final Score Prediction: D-backs 5, Guardians 4
Lean: Arizona (-114)
Total: Over 8.5 (-119)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
