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Baltimore (0-0-0) at Buffalo (0-0-0)
- When: Sep 7 2025, 8:20 PM
- Where: Highmark Stadium, Orchard Park, NY
- Where to watch: NBC
- Last Meeting: BUF 27-25, January 19th, 2025
Baltimore vs Buffalo Preview & Prediction
Spread: Baltimore -1.5
Moneyline: Baltimore -125
Total: 51.0
Baltimore Ravens: Revenge and Run Game Firepower
Baltimore enters this primetime clash with MVP Lamar Jackson running the show and plenty of fire in their gut. The Ravens’ offense was electric last season, topping 424 yards per game while balancing air and ground attacks better than anyone in football. Now they’ve bulked up the defense by adding Jaire Alexander and rookie Malaki Starks, fortifying a unit already built to dominate against the run.
Jackson burned Buffalo with five total touchdowns in two meetings last year, and with Derrick Henry ready to pound defenses, Baltimore’s offensive ceiling remains sky-high. Tight end Mark Andrews looks for personal redemption after a late playoff drop, while the Ravens lean on Roquan Smith to set the tone against Buffalo’s versatile attack.
Player Prop to Watch: Lamar Jackson — Over 235.5 Passing Yards
Buffalo Bills: Allen’s MVP Swagger at Home
The Bills counter with reigning MVP Josh Allen, who racked up 61 more total touchdowns than Lamar since entering the league. Allen is Buffalo’s engine, and his dual-threat skillset makes him a nightmare for any defense. Despite losing key defensive backs to injuries and reshuffling their kicker situation with Matt Prater, Buffalo still has the offensive weapons to keep pace.
James Cook remains vital after tying for the league lead in rushing touchdowns last season, while new addition Joey Bosa should boost the pass rush if he gets rolling. But the Bills’ secondary depth could be tested early and often by Baltimore’s receivers and tight ends.
Player Prop to Watch: Josh Allen — Over 31.5 Rushing Yards
NFL Expert Prediction
This game has shootout written all over it, even with defensive upgrades on both sides. Lamar and Allen both thrive under the bright lights, but Baltimore’s ability to dictate tempo with the run game might be the difference.
Final Score: Ravens 31, Bills 28
Lean: Baltimore -1.5
Total: Over 51.0
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
