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Kansas City vs NY Giants NFL Props & Picks on Patrick Mahomes

The Kansas City Chiefs and the New York Giants will meet on the field at MetLife Stadium.

(Photo by Getty Images) Patrick Mahomes
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Kansas City (0-2-0) at NY Giants (0-2-0)

  • When: Sep 21 2025, 8:20 PM
  • Where: MetLife Stadium, East Rutherford, NJ
  • Where to watch: NBC

Game Odds, Spread, Moneyline & Total

Kansas City Chiefs @ New York Giants
Moneyline

Kansas City Chiefs   -320
New York Giants   +260

Kansas City Chiefs @ New York Giants
Point Spread

Kansas City Chiefs   -6.0 (-115)
New York Giants   6.0 (-105)

Kansas City Chiefs @ New York Giants
Total

Over   44.5 (-115)
Under   44.5 (-105)

Patrick Mahomes NFL Preview & Props

Patrick Mahomes heads into Week 3 with all eyes on him as the Chiefs look to bounce back. The reigning MVP remains one of the league’s most dynamic quarterbacks, blending pinpoint accuracy with playmaking flair. Facing the Giants, Mahomes’ leadership and offensive command will be pivotal as Kansas City seeks to steady its start.

Kansas City Chiefs @ New York Giants
Anytime Touchdown Scorer

Patrick Mahomes (KC)   +330

Kansas City Chiefs @ New York Giants
Who will Score 2 or more Touchdowns?

Patrick Mahomes (KC)   +2200

Kansas City Chiefs @ New York Giants
To Score 3 or more Touchdowns

Patrick Mahomes (KC)   +9000

Kansas City Chiefs @ New York Giants
Result of First Passing Attempt – Patrick Mahomes (KC)

Complete   -310
Incomplete   +220
Interception   +2500

Kansas City Chiefs @ New York Giants
Total Passing Touchdowns – Patrick Mahomes (KC)

Over   1.5 (-160)
Under   1.5 (+120)

Kansas City Chiefs @ New York Giants
Alternate Passing Touchdowns – Patrick Mahomes (KC)

To Record 1+ Passing Touchdowns   -875
To Record 2+ Passing Touchdowns   -160
To Record 3+ Passing Touchdowns   +250
To Record 4+ Passing Touchdowns   +850

Kansas City Chiefs @ New York Giants
Total Passing Attempts – Patrick Mahomes (KC)

Over   34.5 (-115)
Under   34.5 (-115)

Kansas City Chiefs @ New York Giants
Total Completions – Patrick Mahomes (KC)

Over   22.5 (-115)
Under   22.5 (-115)

Kansas City Chiefs @ New York Giants
Longest Pass Completion – Patrick Mahomes (KC)

Over   35.5 (-115)
Under   35.5 (-115)

Kansas City Chiefs @ New York Giants
Total Interceptions Thrown – Patrick Mahomes (KC)

Over   0.5 (+110)
Under   0.5 (-145)

Kansas City Chiefs @ New York Giants
Total Passing Yards – Patrick Mahomes (KC)

Over   229.5 (-135)
Under   229.5 (+105)

Kansas City Chiefs @ New York Giants
Alternate Passing Yards – Patrick Mahomes (KC)

To Record 150+ Passing Yards   -950
To Record 175+ Passing Yards   -460
To Record 200+ Passing Yards   -250
To Record 225+ Passing Yards   -130
To Record 250+ Passing Yards   +150
To Record 275+ Passing Yards   +265
To Record 300+ Passing Yards   +470
To Record 325+ Passing Yards   +800
To Record 350+ Passing Yards   +1200

Kansas City Chiefs @ New York Giants
Who will have more Passing Yards in the game?

Patrick Mahomes (KC)   -130
Russell Wilson (NYG)   EVEN

Kansas City Chiefs @ New York Giants
Total Rush Attempts – Patrick Mahomes (KC)

Over   5.5 (+115)
Under   5.5 (-150)

Kansas City Chiefs @ New York Giants
Longest Rushing Attempt – Patrick Mahomes (KC)

Over   12.5 (-125)
Under   12.5 (-105)

Kansas City Chiefs @ New York Giants
Total Rushing Yards – Patrick Mahomes (KC)

Over   27.5 (-130)
Under   27.5 (EVEN)

Kansas City Chiefs @ New York Giants
Alternate Rushing Yards – Patrick Mahomes (KC)

To Record 10+ Rushing Yards   -1100
To Record 15+ Rushing Yards   -450
To Record 20+ Rushing Yards   -260
To Record 25+ Rushing Yards   -155
To Record 30+ Rushing Yards   -105
To Record 40+ Rushing Yards   +200
To Record 50+ Rushing Yards   +380

Kansas City Chiefs @ New York Giants
Total Passing and Rushing Yards – Patrick Mahomes (KC)

Over   265.5 (-115)
Under   265.5 (-115)

Patrick Mahomes Statistics

Game P. TDs P. Yards INT Comp% Rating
2 2 445 1 58.8 82.0

Patrick Mahomes Past Results

W vs Score Yds Comp % Y/A TD/Int
2 PHI L 17-20 187 55.2 6.4 1/1
1 LAC L 21-27 258 61.5 6.6 1/0

Patrick Mahomes – Last 3 seasons Statistics 

Passing
Year G Comp Att C % Yds Avg Lg TD Int Rate
24-25 16 392 581 67.5 3928 6.8 54 26 11 93.5
23-24 16 401 597 67.2 4183 7.0 67 27 14 92.6
22-23 17 435 648 67.1 5250 8.1 67 41 12 105.2

Rushing/Fumbles
Year G Att Yds Avg TD Fum LOST
24-25 16 58 307 5.3 2 2 0
23-24 16 75 389 5.2 0 5 3
22-23 17 61 358 5.9 4 5 0

NFL Player Props Picks & Predictions

Patrick Mahomes consistently keeps the ball moving, averaging well above 24 completions per game last season. Against a Giants defense still adjusting in coverage, expect Kansas City’s passing volume to flow through Mahomes, making this number very reachable with his efficiency and tempo.

Patrick Mahomes Props Pick: Total Completions – Over 22.5 (-115)
A $115 Bet on that Props will return $215

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