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Cowboys vs Cardinals Odds, Picks & Expert MNF Preview

Expert betting analysis for Cowboys vs Cardinals with odds, matchup insight, and score prediction.

(Photo by Getty Images) CeeDee Lamb
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Arizona (2-5-0) at Dallas (3-4-1)

  • When: Nov 3 2025, 9:15 PM
  • Where: AT&T Stadium, Arlington, TX
  • Where to watch: ABC/ESPN
  • Last Meeting: ARI 28-16, September 24th, 2023

Arizona vs Dallas Preview & Prediction

Spread: Dallas -3.0
Moneyline: Dallas (-175)
Total: 53.5

Arizona Cardinals Betting Outlook

The Cardinals enter Week 9 in desperation mode, riding a five-game losing streak where every defeat has been decided by fewer than three points. Arizona is competitive, but their inability to finish games continues to haunt them.

Kyler Murray could be active, though Jacoby Brissett is set to make his third straight start under center. The veteran has provided a steady hand, throwing for nearly 600 yards in Murray’s absence. Head coach Jonathan Gannon insists the focus is on “controllables” namely cutting down on mental mistakes and finishing drives.

Defensively, veteran Calais Campbell will make his 250th career start, a milestone moment for the 39-year-old defensive end who still plays like he’s 29. The Cardinals have struggled to stop the run, ranking in the bottom third of the league, which could spell trouble against Dallas’ physical offensive front.

Player Prop to Watch: Jacoby Brissett – Over 242.5 Passing Yards – Brissett has quietly been efficient and may need to air it out to keep up with Dallas’ offensive pace.

Dallas Cowboys Betting Outlook

The Cowboys (3-4-1) are coming off a bizarre stretch, a dominant 44-22 win over Washington followed by an ugly 44-24 loss in Denver. Dallas’ inconsistency has been maddening, but their offense still ranks among the league’s elite, and this Monday night matchup is a chance to steady the ship before their bye week.

Head coach Brian Schottenheimer knows his squad has to clean up on both ends of the ball. The defense ranks near the bottom in points allowed, while the offense continues to light up the scoreboard. Dak Prescott and company will look to exploit Arizona’s secondary early and often.

Dallas’ offensive line has been solid, keeping Prescott upright and paving the way for a top-10 rushing attack. However, containing Campbell and Josh Sweat will be crucial to prevent drive-killing sacks.

Player Prop to Watch: CeeDee Lamb – Over 6.5 Receptions – Lamb remains Prescott’s go-to target and should thrive against Arizona’s shaky pass coverage.

Expert Betting Outlook & NFL Prediction

The Cardinals’ luck in close games is bound to run out, and Dallas is eager to prove they’re better than their record suggests. Expect a high-scoring affair with the Cowboys finding enough rhythm to take control late.

Final Score: Cowboys 31, Cardinals 24
Lean: Dallas -3.0
Total: 
Over 53.5 

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