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Pistons vs Bucks Expert Preview and Score Prediction

Detroit vs Milwaukee betting breakdown, odds, and prediction from experts.

(Photo by Getty Images) Cade Cunningham
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Detroit (13-2) at Milwaukee (8-8)

  • When: Nov 22 2025, 8:00 PM
  • Where: Fiserv Forum, Milwaukee, WI, USA
  • TV: FDSDET

Detroit vs Milwaukee Preview & Prediction

Spread: Detroit -8.5
Moneyline: Detroit (-370)
Total: 223.0

Detroit brings a double-digit win streak into Milwaukee, while the Bucks limp in without Giannis. Let’s break this one down.

Detroit Pistons Betting Preview

Detroit rolls into Saturday playing its best basketball in years, ripping off 11 straight wins and looking every bit like a team that finally knows its identity. Their last back-to-back showcased that formula: defend, run, and let Cade Cunningham orchestrate.

Cunningham has been ridiculous out of the gate, putting up elite scoring numbers while nearly averaging a double-double with assists. Jalen Duren has continued to punish teams inside with power and efficiency, and the Pistons’ supporting cast has bought in defensively, allowing their offense to thrive.

Detroit’s challenge here is keeping the foot down on the road against a wounded opponent. With Milwaukee missing its superstar and struggling to close games, the Pistons will look to bury them early. The matchup favors Detroit’s tempo and versatility.

Detroit Player Prop Pick: Cade Cunningham Over 28.5 Points – He’s been cooking for three weeks and carries Detroit’s scoring load with confidence.

Milwaukee Bucks Betting Preview

Milwaukee’s season hit a wall the moment Giannis exited with a groin strain. Without him, they’ve dropped three straight, including Thursday’s overtime loss to Philly where the offense sputtered late.

Ryan Rollins has stepped into a massive workload and responded with a breakout 32-point, 14-assist explosion, but the Bucks simply don’t have the same interior presence or defensive punch without their MVP. Bobby Portis is absorbing the starting role, but the physicality and rim pressure disappear without Giannis’ gravity.

The Bucks’ formula without their star depends heavily on ball movement and perimeter shotmaking, but inconsistency keeps creeping in. With multiple rotation pieces still sidelined, Milwaukee enters this matchup shorthanded and outmatched across several key positions.

Milwaukee Player Prop Pick: Ryan Rollins Over 6.5 Assists – He has the ball nonstop with Giannis out, and the volume alone creates opportunity.

NBA Final Score & Expert Prediction

Detroit is in rhythm, rested, and the deeper, healthier roster. Milwaukee without Giannis simply doesn’t have the firepower to keep pace for four quarters.

Final Score:  Pistons 118, Bucks 106
Lean:  Detroit -8.5
Total: 
Over 223.0 

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