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Siena (23-11) vs Duke (32-2)
- When: Mar 19 2026, 2:50 PM
- Where: Bon Secours Wellness Arena, Greenville, SC, USA
- Where to watch: CBS
(16) Siena vs (1) Duke Preview & Prediction
Spread: Duke -28.0
Moneyline: Duke (-50000)
Total: 135.5
Duke is laying a casual 28 points here. Twenty-eight. That’s not a spread, that’s a warning label. Total sits at 135.5, which basically says “Duke scores, Siena survives.”
Duke Blue Devils: Royalty Rolling In
Duke enters like they always do. No. 1 seed, loaded roster, Final Four expectations, and a fanbase already booking flights.
They’re 32-2, fresh off dominating the ACC, and still somehow dealing with injuries like it’s a side quest. Caleb Foster is out, Patrick Ngongba is probably out, and Duke still looks like a team that could win by accident.
Cameron Boozer is the main problem for Siena. The guy is putting up 22.5 points, 10.2 rebounds, and 4.2 assists per game. Basically, he wakes up and drops a double-double before breakfast.
Then there’s Cayden Boozer, who picked the perfect time to become a thing. Back-to-back 16-point games in the ACC tournament. Because of course Duke has another Boozer ready to ruin your bracket.
Even without full health, Duke has depth, size, talent, and that “we’ve done this before” energy.
Siena Saints: Dream Meets Reality
Siena walks in like the ultimate underdog. 23-11 record, first tournament appearance since 2010, and now they get… this. Congrats, guys.
Led by Gavin Doty at 17.9 points per game, along with Justice Shoats at 13.2 and Francis Folefac at 11.1, Siena actually has some scoring. The problem? They’re about to meet a defense that treats scoring like a personal insult.
This is one of those games where Siena’s goal is simple. Stay competitive, hit some shots, and maybe keep it respectable by halftime. Moral victories are definitely on the table.
But hey, March Madness is chaos, right? Right?
LVSB Prediction
Let’s not overcomplicate this. Duke is better in literally every category except “underdog vibes.”
The only real question is whether Duke goes full throttle for 40 minutes or decides to coast once they’re up 20.
28 points is massive, but Duke has shown they can absolutely bury teams early and never look back.
Final Score: Duke 82, Siena 50
Lean: Duke -28.0
Total: Under 135.5
- NCAAB Odds source: Bovada Sportsbook
