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Houston (20-31) at Chi. Cubs (29-21)
- When: May 22 2026, 2:20 PM
- Where: Wrigley Field, Chicago
- TV: Apple TV+
Game Odds, Runline, Moneyline & Total
Houston Astros @ Chicago Cubs
Moneyline
Houston Astros +124
Chicago Cubs -148
Houston Astros @ Chicago Cubs
Runline
Houston Astros 1.5 (-180)
Chicago Cubs -1.5 (+155)
Houston Astros @ Chicago Cubs
Total
Over 7.0 (-110)
Under 7.0 (-110)
- Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
Spencer Arrighetti MLB Preview & Props
Spencer Arrighetti has been one of the sharpest arms in the Houston Astros rotation this season, attacking hitters with confidence and elite command. His ability to work efficiently through lineups while limiting hard contact has helped him consistently pitch deep into games, making him a major difference-maker on the mound throughout the MLB season.
Houston Astros @ Chicago Cubs
Will Spencer Arrighetti Record a Win?
Yes +200
No -300
Houston Astros @ Chicago Cubs
Total Strikeouts – Spencer Arrighetti (HOU)
Over 5.5 (+120)
Under 5.5 (-160)
Houston Astros @ Chicago Cubs
Alternate Strikeouts – Spencer Arrighetti (HOU)
3+ Strikeouts -2000
4+ Strikeouts -500
5+ Strikeouts -195
7+ Strikeouts +225
8+ Strikeouts +525
Houston Astros @ Chicago Cubs
Total Hits Allowed – Spencer Arrighetti (HOU)
Over 4.5 (+105)
Under 4.5 (-145)
Houston Astros @ Chicago Cubs
Total Pitcher Walks – Spencer Arrighetti (HOU)
Over 2.5 (-170)
Under 2.5 (+130)
Houston Astros @ Chicago Cubs
Total Pitcher Outs – Spencer Arrighetti (HOU)
Over 16.5 (-115)
Under 16.5 (-125)
Spencer Arrighetti Statistics
| Game | WL | ERA | IP | WHIP | K | BB |
| 6 | 5-1 | 1.50 | 36.0 | 1.19 | 35 | 21 |
Spencer Arrighetti Last 10
| Date | Opp | Result | IP | H | R | ER | HR | BB | SO |
| May 15 | vs TEX | W 2-0 |
7.1 | 1 | 0 | 0 | 0 | 4 | 5 |
| May 9 | @CIN | L 3-1 |
5.2 | 5 | 3 | 1 | 0 | 3 | 5 |
| May 2 | @BOS | W 6-3 |
5.0 | 5 | 1 | 1 | 0 | 5 | 4 |
| Apr 26 | vs NYY | W 7-4 |
7.0 | 3 | 1 | 1 | 1 | 1 | 8 |
| Apr 20 | @CLE | W 9-2 |
5.0 | 5 | 2 | 2 | 0 | 4 | 3 |
| Apr 15 | vs COL | W 3-1 |
6.0 | 3 | 1 | 1 | 0 | 4 | 10 |
| Aug 30 | vs LAA | L 4-1 |
6.1 | 1 | 1 | 1 | 1 | 5 | 8 |
| Aug 24 | @BAL | L 3-2 |
5.2 | 6 | 2 | 2 | 1 | 0 | 2 |
| Aug 18 | @DET | L 10-0 |
5.0 | 7 | 5 | 5 | 2 | 4 | 5 |
| Aug 12 | vs BOS | L 14-1 |
5.0 | 1 | 2 | 2 | 0 | 5 | 3 |
- MLB Daily Specials odds & props
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MLB Baseball Props Picks & Predictions
Spencer Arrighetti has been pitching efficiently lately, going over 17 outs in each of his last two starts while maintaining a dominant 1.50 ERA. His ability to limit damage and work deep into games has been a major strength, and against the Chicago Cubs, another lengthy outing looks possible for the Houston Astros.
Spencer Arrighetti Props Pick: Total Pitcher Outs –
Over 16.5 (-115)
A $115 Bet on that Props will return $215
MLB Odds & Props source: Bovada Sportsbook