Sep 23, 2023; East Hartford, Connecticut, USA: In an exciting college football clash, Duke Blue Devils quarterback Riley Leonard (13) scored an impressive touchdown against the UConn Huskies in the second quarter at Rentschler Field at Pratt & Whitney Stadium. This thrilling encounter sets the stage for the Power Five portion of college football’s Week 5, which kicks off with the Louisville Cardinals visiting the North Carolina State Wolfpack. Another marquee matchup in Week 5 showcases the #17 ranked Duke Blue Devils hosting the #11 ranked Notre Dame Fighting Irish. Let’s take a look at the opening odds for college football Week 5.
On Friday night, the Louisville Cardinals (4-0) come in as a 2.5-point favorite after their convincing 56-28 victory over Boston College last Saturday. Meanwhile, the North Carolina State Wolfpack (3-1) secured a close 24-21 win against Virginia on Friday night.
Four games will feature ranked opponents going head-to-head. It all starts with the #10 ranked Utah Utes facing off against the #19 ranked Oregon State Beavers on Friday night. On Saturday, fans can look forward to #24 ranked Kansas Jayhawks challenging the powerhouse #3 ranked Texas Longhorns. The #13 ranked LSU Tigers will take on the #20 ranked Ole Miss Rebels, and the highly-anticipated clash between #11 ranked Notre Dame Fighting Irish and #17 ranked Duke Blue Devils will round off the weekend.
Remember to stay updated with the college football odds throughout the week, as they may change leading up to game time. Below, you can find the full opening odds for Week 5:
College Football
Middle Tennessee State @ Western Kentucky
Middle Tennessee State +225
Western Kentucky -275
Temple @ Tulsa
Temple +160
Tulsa -185
Jacksonville State @ Sam Houston State
Jacksonville State -270
Sam Houston State +220
Louisville @ NC State
Louisville -170
NC State +145
Louisiana Tech @ UTEP
Louisiana Tech -105
UTEP -115
Utah (#10) @ Oregon State (#19)
Utah (#10) +145
Oregon State (#19) -170
Cincinnati @ BYU
Cincinnati +105
BYU -125
Buffalo @ Akron
Buffalo +110
Akron -130
Clemson @ Syracuse
Clemson -240
Syracuse +200
Florida (#22) @ Kentucky
Florida (#22) +125
Kentucky -145
Penn State (#6) @ Northwestern
Penn State (#6) -3500
Northwestern +1100
South Alabama @ James Madison
South Alabama +130
James Madison -150
UAB @ Tulane
UAB +750
Tulane -1400
UL Lafayette @ Minnesota
UL Lafayette +290
Minnesota -380
Utah State @ Connecticut
Utah State -200
Connecticut +170
Kansas (#24) @ Texas (#3)
Kansas (#24) -110
Texas (#3) -110
LSU (#13) @ Mississippi (#20)
LSU (#13) -105
Mississippi (#20) -115
Michigan (#2) @ Nebraska
Michigan (#2) -105
Nebraska -115
Texas A&M @ Arkansas
Texas A&M -245
Arkansas +205
USC (#8) @ Colorado
USC (#8) -1400
Colorado +750
Eastern Michigan @ Central Michigan
Eastern Michigan +255
Central Michigan -310
Virginia @ Boston College
Virginia +130
Boston College -150
Miami Ohio @ Kent State
Miami Ohio -625
Kent State +430
Arizona State @ California
Arizona State +345
California -470
Arkansas State @ Massachusetts
Arkansas State EVEN
Massachusetts -120
Ball State @ Western Michigan
Ball State +105
Western Michigan -125
Baylor @ Central Florida
Baylor +315
Central Florida -420
Bowling Green @ Georgia Tech
Bowling Green +650
Georgia Tech -1100
Georgia (#1) @ Auburn
Georgia (#1) -110
Auburn -110
Houston @ Texas Tech
Houston +275
Texas Tech -350
Illinois @ Purdue
Illinois +105
Purdue -125
Indiana @ Maryland
Indiana +430
Maryland -625
Northern Illinois @ Toledo
Northern Illinois +360
Toledo -500
Old Dominion @ Marshall
Old Dominion +400
Marshall -575
South Florida @ Navy
South Florida +160
Navy -185
Boise State @ Memphis
Boise State +125
Memphis -145
Hawaii @ UNLV
Hawaii +335
UNLV -450
Missouri (#23) @ Vanderbilt
Missouri (#23) -550
Vanderbilt +390
Oregon (#9) @ Stanford
Oregon (#9) -4000
Stanford +1200
Coastal Carolina @ Georgia Southern
Coastal Carolina +235
Georgia Southern -285
East Carolina @ Rice
East Carolina +125
Rice -145
Iowa State @ Oklahoma (#14)
Iowa State +725
Oklahoma (#14) -1300
Texas State @ Southern Mississippi
Texas State -285
Southern Mississippi +235
Troy @ Georgia State
Troy +115
Georgia State -135
Charlotte @ SMU
Charlotte +800
SMU -1600
Michigan State @ Iowa
Michigan State -110
Iowa -110
Notre Dame (#11) @ Duke (#17)
Notre Dame (#11) -220
Duke (#17) +180
South Carolina @ Tennessee (#21)
South Carolina -110
Tennessee (#21) -110
Appalachian State @ UL Monroe
Appalachian State -550
UL Monroe +390
Pittsburgh @ Virginia Tech
Pittsburgh -130
Virginia Tech +110
San Diego State @ Air Force
San Diego State +300
Air Force -400
West Virginia @ TCU
West Virginia +325
TCU -435
Alabama (#12) @ Mississippi State
Alabama (#12) -625
Mississippi State +430
Washington (#7) @ Arizona
Washington (#7) -900
Arizona +575
Nevada @ Fresno State (#25)
Nevada +1000
Fresno State (#25) -2500
Odds source: Bovada Sportsbook
In Week 5, the Oregon Ducks, ranked #9 in the country, emerge as the clear favorites with a 26.5-point spread over the Stanford Cardinal. On the other end of the spectrum, the Utah vs Oregon State matchup starts with even odds.
As the week progresses, it’s important to keep an eye on any line movements that may occur. Don’t miss out on the action by claiming a DraftKings promo code and placing your bets on Week 5 college football games. Additionally, residents of Kentucky can check out DraftKings Kentucky for an exclusive betting experience.
Utah vs Oregon State Early Odds & Prediction:
In their upcoming game at Reser Stadium in Corvallis, the Utah Utes (4-0) square off against the Oregon State Beavers (3-1) on Friday night. Despite Oregon State’s recent loss to Washington State, the oddsmakers have made this matchup a pick’em. Utah’s victory over UCLA allowed them to maintain their unbeaten streak, while Oregon State struggled to defend against Washington State’s potent offense. Missing their injured quarterback Cam Rising, Utah may struggle to contain Oregon State’s DJ Uiagalelei. Therefore, our prediction favors Oregon State in this close battle.
Pick: Oregon State Pk (-110)
Notre Dame vs Duke Early Odds & Prediction:
Initially, a potential showdown
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