San Francisco (19-10) at San Diego (17-11)
- When: Apr 29 2025, 9:40 PM
- Where: PETCO Park, San Diego
- Where to watch: MLBN
Betting Preview, Expert Prediction & Best Player Props: Giants vs. Padres
Odds: San Francisco -125 | Total: 7.0
San Diego Padres Betting Outlook
The Padres are hoping Nick Pivetta continues his scorching start to 2025 as they host the division-leading Giants. Pivetta, a late offseason pickup, has been a revelation on the mound, boasting a 4-1 record and sparkling 1.20 ERA over 30 innings. He’s pitched at least seven scoreless frames in three of five starts, keeping hitters off-balance with sharp command and low walk rates.
Whether it’s due to mechanical tweaks or simply benefiting from pitching in pitcher-friendly Petco Park, Pivetta has looked like a different arm altogether — perhaps even a fringe Cy Young contender. However, he’s struggled historically against the Giants (5.40 ERA in 5 appearances), so regression could be looming, especially with the Padres stuck in a four-game losing skid.
Key Padres Player Prop Picks:
Nick Pivetta – Total Strikeouts Over 5.5
Fernando Tatis Jr. – Total Bases Over 1.5
To snap their losing streak, San Diego will need run support against one of the hottest pitchers in the NL and more timely hitting — something that’s been inconsistent of late.
San Francisco Giants Betting Outlook
San Francisco enters as slight favorites for a reason. They’re on a 5-2 tear and lead the NL West, thanks in large part to Logan Webb, who takes the mound Tuesday. Webb owns a 3-1 record with a 1.98 ERA and has been overpowering hitters with a career-best strikeout rate (44 Ks in 36.1 innings). His ability to keep the ball on the ground and out of the seats makes him a tough matchup, especially in Petco.
Webb has been solid in his career against the Padres (4-3, 2.90 ERA), and he’ll look to keep them cold while continuing to anchor San Francisco’s rotation.
Offensively, the Giants are leaning on Wilmer Flores, who leads MLB with 28 RBIs. While not the flashiest hitter, Flores consistently produces in clutch situations and is a major threat to drive in runs again on Tuesday.
Key Giants Player Prop Picks:
Logan Webb – Total Pitching Outs Over 18.5
Wilmer Flores – To Record an RBI
San Francisco is finding ways to win close games, as evidenced by their 3-2 walk-off win over Texas on Sunday. If Webb sets the tone early, the Giants are in prime position to cash on the moneyline.
Final Score Prediction & Best Bets
Pivetta has been nearly untouchable, but Logan Webb’s consistency, paired with a Giants lineup that has been producing timely offense, gives San Francisco the edge here. Expect a low-scoring pitcher’s duel, with San Francisco doing just enough to take Game 1 of the set.
Final Score: Giants 4, Padres 2
Best Bets: Giants ML (-125)
Total:
Under 7.0 (-120)
Props: Webb Over 18.5 Pitching Outs
- MLB Odds source: MyBookie Sportsbook
