Houston (35-28) at Cleveland (33-29)
- When: Jun 7 2025, 4:10 PM
- Where: Progressive Field, Cleveland
- Where to watch: SCHN
Astros vs. Guardians – Game Betting Preview & Prediction
Moneyline: Houston -114 | Total: 7.0
Houston Astros Overview
Houston continues to heat up, and right-hander Hunter Brown has been leading the charge with a potential All-Star season. Sitting at 8-3 with a microscopic 1.83 ERA, Brown is among the most dominant arms in the league right now. Despite some control hiccups, like four walks in his latest outing, he still held Tampa Bay to just one hit over six shutout innings. That marked his fifth scoreless start of the season.
Brown’s lone prior start against Cleveland was rocky, allowing six earned runs over 5 1/3 innings, but that version of the Guardians isn’t the one he’ll face Saturday. Houston has now won 9 of its last 12, and Jeremy Peña has turned into a force at the plate, boasting a .449 average during a red-hot 12-game hitting streak. With Peña and Jose Altuve (.364 over his last 14 games) locked in, Houston is clicking at the right time.
Cleveland Guardians Breakdown
Cleveland has dropped seven of its last 11 games and is coming off a tough 4-2 loss in the opener, where aggressive base running turned costly early. Still, Jose Ramirez remains scorching hot, riding a 32-game on-base streak and hitting .389 over that stretch. He’s due for a bounce-back after going hitless against Brown in their prior meeting.
Gavin Williams gets the call for the Guardians, and he’s been in excellent form lately, 3-1 with a 2.30 ERA in his last five starts. His last outing featured 6 2/3 innings of work with no earned runs, showcasing improved command and efficiency.
The Guardians will need more timely hitting and better execution against a locked-in Astros team. They’ve played Houston tight in the past, but their inconsistency at the plate could be the difference again.
Betting Outlook & Prediction
Houston’s offense and Brown’s form suggest the Astros are poised to secure a second straight series win on the road. Cleveland keeps it competitive behind Williams but falls short again against Houston’s deeper lineup and sharper bullpen.
Score Prediction: Astros 4, Guardians 2
Side: Houston ML (-114)
Best Bet: Under 7.0 (-101)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
