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Giants vs Dodgers MLB Baseball Odds & Expert Picks

Divisional bragging rights will be on the line when San Francisco and LA Dodgers meet at Dodger Stadium.

(Photo by Getty Images) Dustin May

San Francisco (41-30) at LA Dodgers (42-29)

  • When: Jun 15 2025, 7:10 PM
  • Where: Dodger Stadium, Los Angeles
  • Where to watch: ESPN

Giants vs Dodgers – Game Preview, Prediction and Player Props

Moneyline: LA Dodgers -180 | Total: 9.0

Los Angeles Dodgers Preview

After snapping a rare 10-game home run drought, Shohei Ohtani erupted with two bombs on Saturday, reminding everyone why he’s one of the most feared hitters in baseball. His power surge led the Dodgers to an 11-5 thumping of the Giants, even if the game got a little weird with Enrique Hernández tossing meatballs in mop-up duty.

Now, Los Angeles turns to righty Dustin May (3-4, 4.46 ERA), who hopes to rebound from a rough outing against the Padres. He gave up six runs (five earned) and four walks in five innings. While that wasn’t pretty, May has historically owned the Giants, boasting a 1.62 ERA over five career appearances against them.

The Dodgers are riding momentum, hitting deep, and with the series tied 1-1 and the division lead up for grabs, expect LA to come out swinging.

Dodgers Prop Picks:

Shohei Ohtani Over 1.5 Total Bases – He’s locked in again, and Harrison has been shaky.

Freddie Freeman Over 0.5 RBI – Batting behind Ohtani, he’ll have plenty of chances to drive in runs.

San Francisco Giants Breakdown

Saturday looked like a disaster until Casey Schmitt decided to go video-game mode again, launching his second grand slam in as many days. Unfortunately, both slams came in losing efforts. Still, he made franchise history by being the first Giant ever to hit grand slams in back-to-back games. He’s playing hard, no matter who’s pitching, even if it’s a utility guy.

Left-hander Kyle Harrison (1-1, 4.56 ERA) gets the nod for San Francisco. He’s had a rocky couple of outings, allowing 8 earned runs in his last 9.1 innings. He does have some experience against the Dodgers (0-1, 3.52 ERA in three starts), but he’ll need to be sharp to slow down a red-hot LA lineup.

If Harrison gets into early trouble, this one could get out of hand quickly.

Giants Prop Picks:

Casey Schmitt Over 0.5 Hits – Back-to-back slams? He’s earned the benefit of the doubt.

Thairo Estrada Over 0.5 Runs – Likely to be on base in a game that should see plenty of scoring.

Betting Insight & Prediction

The Dodgers are -180 moneyline favorites, with the total set at 9.0. Given LA’s momentum, May’s success against the Giants, and Harrison’s recent struggles, this game heavily leans in favor of the home team. Expect the Dodgers’ bats to stay hot and the Giants’ late-inning drama to fall short.

Final Score Prediction: Dodgers 7, Giants 4
Lean: LA Dodgers RL -1.5 (+105)
Total: 
Over 9.0 (-110)

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