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Padres vs Nationals MLB Baseball Odds & Parlay Picks

San Diego and Washington will both be trying to pick up a win when they battle at Nationals Park.

(Photo by Getty Images) Yu Darvish
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San Diego (53-44) at Washington (38-59)

  • When: Jul 19 2025, 6:45 PM
  • Where: Nationals Park, Washington
  • Where to watch: SDPA

Padres vs. Nationals – Game Betting Preview & Prediction

Moneyline: San Diego -147 
Spread: San Diego -1.5 (+110)
Total: 9.0

San Diego Padres Preview

The Padres come into Saturday’s matchup riding a wave of momentum after a dramatic 7-2 win Friday night. Manny Machado’s grand slam in the ninth blew the game open, giving San Diego its fourth win in the last five games. Machado’s leadership and power continue to set the tone for the lineup as they chase ground in the NL playoff race.

Yu Darvish (0-1, 6.48 ERA) gets the start for the Padres. He’s still working his way back from elbow inflammation, making just his third start since returning. In his last two outings, he’s struggled with command, allowing six total runs over fewer than 10 innings. Still, Darvish has a history of solid performances against Washington, posting a 2-2 record with a 4.60 ERA in five career starts. The Padres need him to settle in quickly, especially against a Nationals lineup capable of late-inning surprises.

Washington Nationals Preview

The Nationals were competitive Friday, tying the game late with CJ Abrams’ two-run blast, but couldn’t hold off San Diego’s ninth-inning explosion. Washington’s inconsistency on both the bases and defense remains a concern, as seen when Josh Bell’s aggressive baserunning cost them a chance to rally in the seventh inning.

Mitchell Parker (5-10, 5.12 ERA) takes the mound for Washington. He’s been struggling recently, with a 9.28 ERA over his last two starts. Parker’s biggest issue has been giving up runs early, particularly in the first inning, where his season ERA stands at an alarming 8.05. He’s had little success against San Diego, allowing nine runs in just two career starts.

Prediction

The Padres look like the better, more balanced team right now, with their offense coming through in big moments and their bullpen holding steady. Washington’s shaky pitching and defensive miscues make them vulnerable, especially against San Diego’s veteran bats.

Score Prediction: Padres 6, Nationals 4
Pick:  San Diego -1.5 (+110)
Total: Over 9.0 (-115)  

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