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Cincinnati (58-54) at Chi. Cubs (65-46)
- When: Aug 4 2025, 8:05 PM
- Where: Wrigley Field, Chicago
- Where to watch: Marquee Sports Network
Reds vs. Cubs – Game Betting Preview & Prediction
Moneyline: Chi. Cubs -141
Spread: Chi. Cubs -1.5 (+162)
Total: 7.5
Chicago Cubs Betting Preview
The Cubs welcome right-hander Michael Soroka to Wrigley Field as he makes his team debut in Monday’s series opener against the Reds. After being acquired from Washington, Soroka gets a fresh start and a serious upgrade, he’s going from one of MLB’s worst defenses to one of its sharpest. That alone could boost his numbers heading into August.
Chicago is counting on Soroka to stabilize a rotation that’s been hit with inconsistency. Despite his 3-8 record and 4.87 ERA, the Cubs are optimistic. His groundball tendencies should play well in a defense-first system anchored by Dansby Swanson, his former Braves teammate.
The Cubs are slight moneyline favorites, and for good reason: they’re 31-25 at home, have better bullpen depth, and will look to start the series with a bang. They’ll also be motivated to erase the memory of Sunday’s close loss.
Cubs Player to Watch: Seiya Suzuki – has been heating up at the plate and could spark early offense against a lefty.
Cincinnati Reds Betting Preview
The Reds roll into Chicago after a travel-heavy series with the Braves, including a quirky game at Bristol Motor Speedway. Their Sunday loss snapped a mini-streak and now they’ll turn to Nick Lodolo, who has quietly pieced together a strong 2025 campaign.
Lodolo has posted a 3.09 ERA this season and is coming off a dazzling 11-strikeout performance vs. the Dodgers. His July was elite, three wins, sub-2.00 ERA, and dominant stuff. The key will be whether Cincinnati’s bullpen can support him late, something that’s burned them recently.
They’ve been around .500 on the road and may find it tough to generate consistent offense in pitcher-friendly Wrigley with tired legs and shaky momentum.
Reds Player to Watch: Elly De La Cruz – if anyone can flip a game with one swing or one sprint, it’s him.
MLB Betting Prediction
The better defensive club with momentum, and Soroka gets the right matchup to shine. Expect a competitive but controlled total under 7.5 unless Lodolo slips late.
Score Prediction: Cubs 4, Reds 3
Pick: Chi. Cubs (-141)
Total: Under 7.5 (-104)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
