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Tigers vs Royals Betting Preview, Odds and Parlay Prediction

Expert betting preview of Tigers vs Royals with odds, analysis, and final score prediction.

(Photo by Getty Images) Casey Mize
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Kansas City (66-62) at Detroit (76-53)

  • When: Aug 22 2025, 7:10 PM
  • Where: Comerica Park, Detroit
  • Where to watch: Apple TV+

Royals vs. Tigers – Game Betting Preview & Prediction

Moneyline: Detroit -156 
Spread: Detroit -1.5 (+130)
Total: 8.0

Detroit Tigers Betting Preview

The Tigers return home as -156 moneyline favorites, with the total set at 8.0 runs, looking to keep their momentum rolling. Detroit has surged in August, winning nine of its last 11 games, including a dominant sweep of the Astros where their pitching allowed just two runs total.

All-Star Casey Mize (12-4, 3.63 ERA) takes the mound riding a personal three-game win streak. He’s benefitted from explosive run support, with Detroit scoring 23 runs across his last three starts. Mize struck out 10 Twins in his last outing while showing command of his full arsenal. Though his history against Kansas City has been mixed (3-2, 4.99 ERA in 12 career starts), the Tigers’ lineup and bullpen have provided the cushion he needs to succeed.

Kansas City Royals Betting Preview

The Royals are making a late-season push, winning eight of their last 10 games to move within striking distance of an AL wild-card spot. Thursday’s 6-4 win over Texas featured Vinnie Pasquantino’s fourth straight game with a home run, giving Kansas City a dangerous middle-of-the-order presence.

Rookie Ryan Bergert (1-1, 2.75 ERA) gets the ball, making just his fourth start since being acquired from San Diego. Despite limited MLB experience, he’s shown poise, lasting into the sixth inning each time out and keeping opponents off balance. Kansas City will rely heavily on his composure as they try to chip away at Detroit’s 9.5-game division lead.

MLB Betting Outlook & Prediction

This series opener has all the feel of a playoff-level matchup, with Detroit holding the edge thanks to Mize’s current form and their red-hot stretch at the plate. Kansas City is dangerous with Pasquantino swinging a hot bat, but Detroit’s home advantage and steady ace make the difference here.

Score Prediction: Tigers 5, Royals 3
Pick: Detroit -1.5 (+130)
Total: Under 8.5 Alt Lines (-130) 

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