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Chi. Cubs (76-55) at San Francisco (63-68)
- When: Aug 26 2025, 9:45 PM
- Where: Oracle Park, San Francisco
- Where to watch: Marquee Sports Network
Cubs vs Giants – Game Preview, Prediction and Player Props
Moneyline: Chi. Cubs -139
Total: 7.5
RunLine: Chi. Cubs -1.5 (+131)
Chicago Cubs Betting Outlook
The Cubs enter this series as -139 moneyline favorites with the total set at 7.5 runs. Riding momentum from a three-game sweep of the Angels, Chicago has now won six of their last seven and trimmed the Brewers’ NL Central lead. Matthew Boyd (12-6, 2.61 ERA) takes the mound, making his first career start at Oracle Park. Earlier this season, Boyd held San Francisco to two runs across six innings in a 9-2 win.
Kyle Tucker just erupted for five hits and three homers in a 19-run explosion against Los Angeles, signaling that the Cubs’ offense is heating up at the right time. Against Verlander, though, Tucker has been quiet (1-for-5 lifetime), but Chicago’s lineup overall should provide enough support.
Player Prop to Watch (Cubs): Kyle Tucker Over 1.5 Total Bases – He’s locked in, coming off a monster series.
San Francisco Giants Betting Outlook
San Francisco avoided a complete collapse in Milwaukee with a late rally, taking two of three from the Brewers to keep faint playoff hopes alive. They return home just 6.5 games out of the final wild-card spot, but home field has been brutal, the Giants have dropped 15 of their last 17 at Oracle Park.
Justin Verlander (1-10, 4.64 ERA) gets the ball, looking to end a frustrating season on a high note. The 42-year-old hasn’t lost to the Cubs in his career, going 2-0 with a 2.35 ERA in four starts. He’s also sitting on 99 strikeouts this season, one shy of his 17th campaign with 100 or more, which could add fuel to his performance. Willy Adames has been a spark recently, delivering clutch hits and leadership during their road trip.
Player Prop to Watch (Giants): Justin Verlander Over 4.5 Strikeouts – History and motivation push him toward a milestone night.
MLB Prediction & Betting Angle
The Cubs are hot, and Boyd has been reliable all season, while the Giants continue to stumble at home. Verlander may keep it close early, but Chicago’s lineup depth should prevail against San Francisco’s struggling bats.
Final Score Prediction: Cubs 5, Giants 3
Lean: Chi. Cubs -1.5 (+131)
Total: Over 7.5 (-116)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
