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Chi. Cubs (76-57) at San Francisco (65-68)
- When: Aug 28 2025, 3:45 PM
- Where: Oracle Park, San Francisco
- Where to watch: Marquee Sports Network-Chicago
Cubs vs. Giants – Game Betting Preview & Prediction
Moneyline: San Francisco -110
Spread: San Francisco -1.5 (+180)
Total: 7.0
Chicago Cubs Betting Outlook
The Cubs entered this series feeling confident after sweeping three games from the Angels, but back-to-back losses in San Francisco have dimmed their outlook. Instead of gaining ground in the NL Central, they now sit 6.5 games behind Milwaukee and hold only a 1.5-game cushion over San Diego for the final NL Wild Card spot.
Thursday’s finale puts Shota Imanaga (8-6, 3.03 ERA) on the hill. While the lefty hasn’t won a game this month, it’s not for lack of performance, he’s carrying a 2.33 ERA in August across four starts. The problem has been run support, with just seven total runs of backing in that stretch. Chicago needs its bats to step up to avoid a sweep, especially since Imanaga has shown consistency in limiting damage.
San Francisco Giants Betting Outlook
The Giants, once stumbling through the summer, suddenly look alive. Winners of four straight, San Francisco has overtaken Arizona for third in the NL West. They remain seven games out of the Wild Card, but recent performances have injected energy into the clubhouse.
Much of that has come from Rafael Devers, who exploded on Wednesday with two homers and five RBIs in a 12-3 rout. His presence has made the lineup more dangerous, with Heliot Ramos and Matt Chapman also contributing in big spots. On the mound, Logan Webb (12-9, 3.13 ERA) takes charge. The Giants’ ace has allowed just one run in his last two outings (13 innings), helping San Francisco win both convincingly. He’s 2-1 lifetime against the Cubs.
MLB Final Betting Outlook
San Francisco has both momentum and their ace on the mound, while the Cubs’ offense has gone cold at the wrong time. Imanaga has pitched well, but his lack of run support makes it tough to trust Chicago here. With Webb dialed in and the Giants’ bats heating up, the edge leans San Francisco.
Score Prediction: Giants 4, Cubs 2
Pick: San Francisco (-110)
Total: Under 7.0 (-103)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
