Kansas City vs LA Chargers NFL Props & Picks on Patrick Mahomes

(Photo by Getty Images) Patrick Mahomes

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Kansas City (0-0) at LA Chargers (0-0)

• When: Sep 5 2025, 8:00 PM
• Where: Corinthians Arena, Corinthians Arena
• Where to watch: YouTube

Game Odds, Spread, Moneyline & Total

Kansas City Chiefs @ Los Angeles Chargers
Moneyline
Kansas City Chiefs   -165
Los Angeles Chargers   +140

Kansas City Chiefs @ Los Angeles Chargers
Point Spread
Kansas City Chiefs   -3.0 (-110)
Los Angeles Chargers   3.0 (-110)

Kansas City Chiefs @ Los Angeles Chargers
Total
Over   47.0 (EVEN)
Under   47.0 (-120)

• Odds source: Bovada Sportsbook
• Get real-time live scores & latest betting odds here!

Patrick Mahomes NFL Preview & Props

Patrick Mahomes enters the new NFL season as the unquestioned standard for quarterbacks and bettors alike. His consistency, creativity, and command of Andy Reid’s offense make him one of the most reliable options on the board. With elite decision-making, mobility, and unmatched improvisation, Mahomes continues to shape betting markets weekly. Handicappers know his track record against top defenses, especially divisional opponents, creates value opportunities, making him a centerpiece for any serious NFL analysis this year.

Kansas City Chiefs @ Los Angeles Chargers
Anytime Touchdown Scorer
Patrick Mahomes (KC)   +525

Kansas City Chiefs @ Los Angeles Chargers
Who will Score 2 or more Touchdowns?
Patrick Mahomes (KC)   +5500

Kansas City Chiefs @ Los Angeles Chargers
Total Passing Touchdowns – Patrick Mahomes (KC)
Over   1.5 (-120)
Under   1.5 (-110)

Kansas City Chiefs @ Los Angeles Chargers
Alternate Passing Touchdowns – Patrick Mahomes (KC)
To Record 1+ Passing Touchdowns   -825
To Record 2+ Passing Touchdowns   -150
To Record 3+ Passing Touchdowns   +260
To Record 4+ Passing Touchdowns   +800

Kansas City Chiefs @ Los Angeles Chargers
Total Passing Attempts – Patrick Mahomes (KC)
Over   34.5 (-135)
Under   34.5 (+105)

Kansas City Chiefs @ Los Angeles Chargers
Total Completions – Patrick Mahomes (KC)
Over   23.5 (-130)
Under   23.5 (EVEN)

Kansas City Chiefs @ Los Angeles Chargers
Longest Pass Completion – Patrick Mahomes (KC)
Over   36.5 (-110)
Under   36.5 (-120)

Kansas City Chiefs @ Los Angeles Chargers
Total Interceptions Thrown – Patrick Mahomes (KC)
Over   0.5 (EVEN)
Under   0.5 (-130)

Kansas City Chiefs @ Los Angeles Chargers
Total Passing Yards – Patrick Mahomes (KC)
Over   243.5 (-115)
Under   243.5 (-115)

Kansas City Chiefs @ Los Angeles Chargers
Alternate Passing Yards – Patrick Mahomes (KC)
To Record 150+ Passing Yards   -1600
To Record 175+ Passing Yards   -700
To Record 200+ Passing Yards   -375
To Record 225+ Passing Yards   -195
To Record 250+ Passing Yards   -105
To Record 275+ Passing Yards   +175
To Record 300+ Passing Yards   +300
To Record 325+ Passing Yards   +525
To Record 350+ Passing Yards   +875

Kansas City Chiefs @ Los Angeles Chargers
Who will have more Passing Yards in the game?
Patrick Mahomes (KC)   -130
Justin Herbert (LAC)   EVEN

Kansas City Chiefs @ Los Angeles Chargers
Total Rush Attempts – Patrick Mahomes (KC)
Over   3.5 (-105)
Under   3.5 (-125)

Kansas City Chiefs @ Los Angeles Chargers
Longest Rushing Attempt – Patrick Mahomes (KC)
Over   9.5 (-125)
Under   9.5 (-105)

Kansas City Chiefs @ Los Angeles Chargers
Total Rushing Yards – Patrick Mahomes (KC)
Over   17.5 (-115)
Under   17.5 (-115)

Kansas City Chiefs @ Los Angeles Chargers
Alternate Rushing Yards – Patrick Mahomes (KC)
To Record 25+ Rushing Yards   +170
To Record 40+ Rushing Yards   +500
To Record 50+ Rushing Yards   +1000

Kansas City Chiefs @ Los Angeles Chargers
Total Passing and Rushing Yards – Patrick Mahomes (KC)
Over   265.5 (-115)
Under   265.5 (-115)

Patrick Mahomes Statistics

Game	P. TDs	P. Yards	INT	Comp%	Rating
16	26	3928	11	67.5	93.5

Patrick Mahomes Past Results

W	vs	Score	Yds	Comp %	Y/A	TD/Int
Post	@ PHI	L 22-40	257	65.6	8.0	3/2
Post	BUF	W 32-29	245	69.2	9.4	1/0
Post	HOU	W 23-14	177	64.0	7.1	1/0
18	@ DEN	L 0-38	–	–	–	–
17	@ PIT	W 29-10	320	76.3	8.4	3/0
16	HOU	W 27-19	260	68.3	6.3	1/0
15	@ CLE	W 21-7	159	50.0	4.2	2/0
14	LAC	W 19-17	210	64.9	5.7	1/0
13	LV	W 19-17	306	56.5	6.7	1/0
12	@ CAR	W 30-27	269	73.0	7.3	3/0
11	@ BUF	L 21-30	196	69.7	5.9	3/2
10	DEN	W 16-14	266	66.7	6.3	1/0
9	TB	W 30-24	291	77.3	6.6	3/0
8	@ LV	W 27-20	262	71.1	6.9	2/1
7	@ SF	W 28-18	154	59.3	5.7	0/2
5	NO	W 26-13	331	71.8	8.5	0/1
4	@ LAC	W 17-10	245	65.5	8.4	1/1
3	@ ATL	W 22-17	217	66.7	5.6	2/1
2	CIN	W 26-25	151	72.0	6.0	2/2
1	BAL	W 27-20	291	71.4	10.4	1/1

NFL Player Props Picks & Predictions

Patrick Mahomes thrives against AFC West rivals, especially the Chargers, with 27 career TD passes in 12 meetings. Even with questions at wide receiver, his chemistry with Travis Kelce and Kansas City’s aggressive red-zone approach make Over 1.5 passing touchdowns a strong angle for Week 1’s Brazil opener.

Patrick Mahomes Props Pick: Total Passing Touchdowns – Over 1.5 (-120)
A $120 Bet on that Props will return $220

• NFL Props source: Bovada Sportsbook

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