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Mets vs Padres: Who Wants October More Tonight?

Mets vs Padres betting preview with odds, analysis, and score prediction.

(Photo by Getty Images) Clay Holmes
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San Diego (82-68) at NY Mets (77-73)

  • When: Sep 16 2025, 7:10 PM
  • Where: Citi Field, Flushing, Queens
  • Where to watch: TBS

Both Clubs Chasing Wins Like it’s the Last Slice of Pizza

Moneyline: NY Mets -114 
Spread: NY Mets -1.5 (+165)
Total: 8.0

San Diego Padres Outlook

The Padres (82–68) have been grinding their way through September, and somehow they look like the friend who shows up late to the party but still manages to steal the last slice of pizza. On the road, however, they’ve been more “lost tourist” than contender, sporting a 35–40 mark away from home.

Michael King (4–2, 2.87 ERA) takes the hill and has quietly been dealing like a blackjack pro on a heater. His command and ability to keep hitters off balance have been a major asset down the stretch. If San Diego wants to spoil the Mets’ night, King will need to be sharp against a New York lineup that is streakier than a broken slot machine.

Luis Arraez, meanwhile, continues to be the contact machine that makes hitting look effortless. Rookie Jackson Merrill has been the spark lately, flashing pop with four homers in his last 10 games. Together, they’ve been just enough offense to keep San Diego relevant in the wild-card picture.

New York Mets Outlook

The Mets (77–73) are hanging around in the NL East like that one guest who won’t leave the party, even though the host is already cleaning up. At home, though, they’ve been tough to beat, posting a 46–29 record in Queens.

Clay Holmes (11–8, 3.75 ERA) gets the ball, and while he won’t be mistaken for an ace, he’s been reliable enough to keep the Mets in ballgames. New York desperately needs a solid outing from him, especially with their recent 2–8 skid, during which they’ve been outscored by 23 runs. Ouch.

Juan Soto has been the lone bright spot, launching 40 home runs while carrying the offense on his back like a human Uber. Brett Baty has chipped in lately as well, though his contributions look more like seasoning than the main course.

For the Mets, the formula is simple: score five runs and they’re practically unbeatable (53–13 in such games). Anything less, and Citi Field fans may need extra hot dogs just to cope.

Prediction & Betting Angle

The Mets are slight moneyline favorites at -114, with the total set at 8.0 runs. New York’s home record plus Soto’s hot bat give them the edge, but the Padres’ momentum can’t be ignored. With both pitchers steady, expect some tense innings before late scoring swings the outcome.

Score Prediction: Mets 5, Padres 4
Pick: NY Mets (-114)
Total: Over 8.0 (-119) 

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