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Mets vs Padres Odds, Prediction & Betting Preview

Expert Mets vs Padres betting preview with odds, key matchups, and predictions in Thursday’s NL wild-card showdown.

(Photo by Getty Images) Jonah Tong
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San Diego (83-69) at NY Mets (78-74)

  • When: Sep 18 2025, 1:10 PM
  • Where: Citi Field, Flushing, Queens
  • Where to watch: SNY

Padres vs. Mets – Game Betting Preview & Prediction

Moneyline: NY Mets -130 
Spread: NY Mets -1.5 (+145)
Total: 9.0

Game Odds & Overview

The New York Mets are set as -130 moneyline favorites with the total sitting at 9.0 runs in Thursday’s matinee finale against the San Diego Padres. Both teams remain deep in the National League wild-card chase, making this matchup a high-stakes affair.

New York Mets Betting Outlook

The Mets (78-74) are clinging to the final NL wild-card slot despite a brutal stretch since mid-June. Wednesday’s 7-4 loss reminded fans of their inconsistency, but New York still holds a slim lead over the Diamondbacks, Reds, and Giants.

Rookie Jonah Tong (1-2, 8.49 ERA) will make his fourth career start, searching for stability after a disastrous outing against Texas where he lasted less than an inning. Tong has yet to face San Diego, and the Mets desperately need him to steady the ship.

New York’s offense continues to lean heavily on Juan Soto, who has shown power but also missed chances in key moments. To keep their playoff hopes intact, the Mets must strike early and avoid leaning too heavily on their shaky bullpen.

San Diego Padres Betting Outlook

The Padres (83-69) have momentum, winning seven of their last 11 and holding firm in the second NL wild-card spot. They also remain within striking distance of the division-leading Dodgers. Wednesday’s victory, highlighted by Manny Machado’s grand slam, showed San Diego’s ability to capitalize on New York’s pitching flaws.

Randy Vasquez (5-6, 3.72 ERA) takes the mound, fresh off a gem where he struck out nine Rockies in six scoreless innings. He’s never faced the Mets, but his recent form suggests he’s ready to handle the challenge. San Diego’s bullpen management also looks playoff-ready, with Mike Shildt pulling strings aggressively in high-leverage moments.

MLB Prediction & Betting Angle

With San Diego’s offense clicking and Vasquez trending upward, the Padres look like the steadier side. The Mets are fighting for their playoff lives but may struggle with Tong’s inexperience on the mound.

Score Prediction: Padres 6, Mets 4
Pick: San Diego (+111)
Total: Over 9.0 (-111) 

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