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Cubs vs Mets Odds, Expert Picks & Betting Preview

Handicappers preview Cubs vs Mets with odds, analysis, and expert score prediction for Thursday night’s clash

(Photo by Getty Images) Shota Imanaga
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NY Mets (81-77) at Chi. Cubs (89-69)

  • When: Sep 25 2025, 7:40 PM
  • Where: Wrigley Field, Chicago
  • Where to watch: SNY

Mets vs Cubs – Game Preview, Prediction and Player Props

Moneyline: NY Mets -111
Total: 7.5
RunLine: NY Mets -1.5 (+150)

Chicago Cubs Betting Outlook

The Cubs already punched their playoff ticket for the first time in five years, but they’re not cruising into October just yet. After snapping a five-game losing streak with a dominant 10–3 win on Wednesday, Chicago has its eyes set on securing home-field advantage in the wild-card round.

Shota Imanaga (9-7, 3.37 ERA) gets the start, but the lefty has been plagued by the long ball. He’s given up 10 homers in his last five outings, including three in his most recent start. Against the Mets, his career ERA sits at a bloated 9.00 across two starts, so limiting mistakes will be crucial.

The offense has done its part lately. Pete Crow-Armstrong’s heads-up baserunning Wednesday was symbolic of the Cubs’ energy, this team isn’t satisfied with just making the playoffs. They want Wrigley Field rocking in October.

Cubs Player Prop Pick: Pete Crow-Armstrong Over 0.5 Runs Scored – with Chicago’s offense clicking, his on-base ability sets him up to cross the plate.

New York Mets Betting Outlook

The Mets are clinging desperately to the final NL wild-card spot at 81–77, but recent form has been ugly. They’ve dropped 12 of their last 17 games, often falling into early deficits. Francisco Alvarez has been a bright spot, homering in back-to-back games, while Juan Soto continues to mash with 43 bombs on the season.

Nolan McLean (4-1, 1.27 ERA) will take the mound in the series finale. The rookie has been sharp, keeping the ball in the park with only one homer allowed across seven outings. While his winless streak sits at three, he’s held opponents in check and deserves better support from the lineup.

For New York, every game is must-win. With the Diamondbacks and Reds breathing down their necks, the Mets can’t afford another letdown.

Mets Player Prop Pick: Francisco Alvarez Over 1.5 Total Bases – he’s heating up at the plate and could be the key bat to spark New York’s offense.

MLB Expert Betting Prediction

The Mets are slight favorites at -111 with the total at 7.5. Imanaga’s home-run struggles make the Cubs risky to back, while McLean has been quietly reliable for New York. With playoff urgency on their side, the Mets’ edge on the mound is hard to ignore.

A tight contest, but New York finds just enough offense to hold onto their playoff position while the Cubs look ahead to October.

Final Score Prediction: Mets 5, Cubs 4
Lean: NY Mets (-111)
Total: 
Over 7.5 (-110) 

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