Arizona (31-31) at Cincinnati (30-33)
- When: Jun 6 2025, 7:10 PM
- Where: Great American Ball Park, Cincinnati
- Where to watch: Apple TV+
Diamondbacks vs. Reds – Game Betting Preview & Prediction
Moneyline: Arizona -115 | Total: 9.5
Arizona Diamondbacks: Riding the Wave
Arizona just pulled off one of the wildest wins in franchise history, rallying for seven runs in the ninth to stun Atlanta and complete a sweep. It marked their largest ninth-inning comeback ever and sent them into Cincinnati on a four-game heater, their longest streak since mid-April.
Eugenio Suarez was the hero on Thursday with a clutch two-run double that capped the madness, and the D-backs now look to keep that momentum rolling. The club hands the ball to Eduardo Rodriguez, who returns from a stint on the IL. The lefty hasn’t looked sharp this season (7.05 ERA) but has shown flashes, including a strong rehab start where he struck out nine in under five innings.
Arizona swept the Reds last time they visited Cincy and holds a 5-1 record in their last six meetings, making them a trendy moneyline option here.
Cincinnati Reds: In Need of Answers
The Reds are spiraling again after briefly climbing above .500. They’ve dropped four of their last five, and injuries continue to bite, especially with Hunter Greene landing back on the IL due to a nagging groin issue. Cincinnati’s bullpen has been solid, and their .231 opposing batting average is one of the league’s best, but their offense has struggled to provide any consistent support.
Nick Lodolo gets the nod for Friday’s opener. He’s quietly been a bright spot, putting up a 3.10 ERA, including a dominant six-inning shutout against the Cubs in his last start. But the Reds gave him no run support in that one, and that’s been the theme lately.
Despite their strong pitching metrics, Cincinnati hasn’t figured out how to beat Arizona lately, having lost five of six to them last season.
Betting Outlook & Prediction
Arizona has the hotter bats, the momentum, and the confidence. Even with Rodriguez returning from injury, the Diamondbacks should be able to generate enough offense to sneak past the Reds, especially if Lodolo doesn’t get help.
Score Prediction: Diamondbacks 6, Reds 4
Side: Arizona ML (-115)
Best Bet: Over 9.5 (+102)
Lean Arizona and consider the Over with both teams rolling out lefties in a hitter-friendly park.
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
