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Medvedev vs Tiafoe US Open Matchup
Matchup: (7) Daniil Medvedev vs (11) Frances Tiafoe
When: Sep 6 2026, at 3:00 PM – approximately
Tournament: US Open
Stage: Round of 16
Venue: Louis Armstrong Stadium
Location: New York City, New York
Tennis Match Odds, Spread, Moneyline & Total
Daniil Medvedev vs Frances Tiafoe
Game Spread
Daniil Medvedev -2.5 (-120)
Frances Tiafoe 2.5 (-110)
Daniil Medvedev vs Frances Tiafoe
Moneyline
Daniil Medvedev -170
Frances Tiafoe +140
Daniil Medvedev vs Frances Tiafoe
Total
Over 39.5 (-115)
Under 39.5 (-115)
Go to the Prediction here
(Get real-time live scores & latest betting odds here!)
Medvedev vs Tiafoe ATP Tennis Preview
Daniil Medvedev meets Frances Tiafoe in Sunday’s US Open Round of 16 at Louis Armstrong Stadium. Medvedev owns a dominant 6-1 head-to-head edge, has yet to drop a set in New York, and brings 20 career hard-court titles into the matchup.
Tiafoe counters with home-crowd energy and a strong 2026 campaign, but he has spent considerably more time on court. Medvedev’s elite return game, deep positioning and superior matchup history make him the stronger betting side. Tiafoe can keep sets competitive, but Medvedev’s moneyline and game spread deserve the most attention.
Medvedev vs Tiafoe Matchups Props
Daniil Medvedev vs Frances Tiafoe
Game Spread
Daniil Medvedev – S1 -1.5 (+105)
Frances Tiafoe – S1 1.5 (-135)
Daniil Medvedev vs Frances Tiafoe
Moneyline
Daniil Medvedev – S1 -145
Frances Tiafoe – S1 +110
Daniil Medvedev vs Frances Tiafoe
Total
Over – S1 10.5 (+220)
Under – S1 10.5 (-300)
Daniil Medvedev vs Frances Tiafoe
Match Specials
Medvedev To Win & Over 39.5 Total Games +210
Medvedev To Win & Under 39.5 Total Games +210
Tiafoe To Win & Over 41.5 Total Games +325
Tiafoe To Win & Under 41.5 Total Games +300
Medvedev To Win Every Set 6-0, 6-1 or 6-2 +45000
Medvedev To Win Every Set 6-3 or 6-4 +4000
Medvedev To Win Every Set 7-5 or 7-6 +15000
Medvedev To Win Every Set 7-6 +55000
Tiafoe To Win Every Set 6-0, 6-1 or 6-2 +100000
Tiafoe To Win Every Set 6-3 or 6-4 +8000
Tiafoe To Win Every Set 7-5 or 7-6 +27500
Tiafoe To Win Every Set 7-6 +65000
Both Players Opening Service Games To Go To Deuce +1200
Both Players To Face A Break Point In Their Opening Service Game +750
Match To Go To A Final Set Tie Break +1200
Medvedev To Break Serve In The 1st Set -250
Tiafoe To Break Serve In The 1st Set -185
Both Players To Break Serve In The 1st Set +135
Medvedev To Break Serve In Sets 1 & 2 -105
Tiafoe To Break Serve In Sets 1 & 2 +135
Medvedev To Win A Point In Each of His First 4 Return Games -135
Tiafoe To Win A Point In Each of His First 4 Return Games -110
Over 18.5 Total Games In Set 1 & 2 Combined -200
Under 18.5 Total Games In Set 1 & 2 Combined +150
Medvedev To Win His 1st Service Game, 1st Set & Match +135
Tiafoe To Win His 1st Service Game, 1st Set & Match +225
Medvedev To Break Serve 1st, Win 1st Set & Match +160
Tiafoe To Break Serve 1st, Win 1st Set & Match +260
Medvedev To Win & A Tie Break In the Match +165
Medvedev To Win & No Tie Break In the Match +260
Tiafoe To Win & A Tie Break In the Match +230
Tiafoe To Win & No Tie Break In the Match +400
Medvedev To Win & A Tie Break In the 1st Set +575
Tiafoe To Win & A Tie Break In the 1st Set +750
Medvedev To Lead 3-1 After 4 Games In Sets 1 & 2 +1200
Medvedev To Lead 4-2 After 6 Games In Sets 1 & 2 +1000
Tiafoe To Lead 3-1 After 4 Games In Sets 1 & 2 +1750
Tiafoe To Lead 4-2 After 6 Games In Sets 1 & 2 +1500
Medvedev To Win 1st Set 7-6 & Win The Match +875
Tiafoe To Win 1st Set 7-6 & Win The Match +1100
Medvedev To Win 1st Set 6-0 & Win The Match +5500
Tiafoe To Win 1st Set 6-0 & Win The Match +8000
Medvedev To Win The First 8 Points of The Match +20000
Tiafoe To Win The First 8 Points of The Match +25000
Each of The 1st Two Sets To End In A Tie Break +1500
1-1 After 2 Games In Each Of The 1st 2 Sets -150
2-2 After 4 Games In Each Of The 1st 2 Sets +200
3-3 After 6 Games In Each Of The 1st 2 Sets +350
Both Players To Win A Set & No Tie Break In The Match +300
Both Players To Win A Set & A Tie Break In The Match -105
Both Players To Win A Set & 2+ Tie Breaks In The Match +400
Over 8.5 Games In Each of Sets 1 & 2 -230
Over 9.5 Games In Each of Sets 1 & 2 +175
Over 10.5 Games In Each of Sets 1 & 2 +800
Under 8.5 Games In Each of Sets 1 & 2 +1500
Under 9.5 Games In Each of Sets 1 & 2 +325
Under 10.5 Games In Each of Sets 1 & 2 -120
Daniil Medvedev vs Frances Tiafoe
Alternate Total Games
Over 38.5 (-130)
Under 38.5 (EVEN)
Over 39.0 (-125)
Under 39.0 (-105)
Over 40.0 (-105)
Under 40.0 (-125)
Over 40.5 (+105)
Under 40.5 (-135)
Over 41.5 (+120)
Under 41.5 (-155)
Daniil Medvedev vs Frances Tiafoe
Alternate Total Games
Over – S1 8.5 (-435)
Under – S1 8.5 (+290)
Over – S1 12.5 (+350)
Under – S1 12.5 (-550)
Daniil Medvedev vs Frances Tiafoe
Total Games O/U – Daniil Medvedev
Over 20.5 (-115)
Under 20.5 (-115)
Daniil Medvedev vs Frances Tiafoe
Total Games O/U – Frances Tiafoe
Over 19.5 (-110)
Under 19.5 (-120)
Daniil Medvedev vs Frances Tiafoe
Total Games O/U
Over – S1 9.5 (-145)
Under – S1 9.5 (+110)
Daniil Medvedev vs Frances Tiafoe
Alternate Game Spread
Daniil Medvedev -1.5 (-145)
Frances Tiafoe 1.5 (+110)
Daniil Medvedev -2.0 (-130)
Frances Tiafoe 2.0 (EVEN)
Daniil Medvedev -3.0 (-105)
Frances Tiafoe 3.0 (-125)
Daniil Medvedev -3.5 (+105)
Frances Tiafoe 3.5 (-135)
Daniil Medvedev -4.5 (+135)
Frances Tiafoe 4.5 (-175)
Daniil Medvedev vs Frances Tiafoe
Alternate Game Spread
Daniil Medvedev – S1 1.5 (-205)
Frances Tiafoe – S1 -1.5 (+155)
Daniil Medvedev – S1 -3.5 (+550)
Frances Tiafoe – S1 3.5 (-1000)
Daniil Medvedev – S1 3.5 (-1400)
Frances Tiafoe – S1 -3.5 (+700)
Daniil Medvedev vs Frances Tiafoe
Set Betting
Daniil Medvedev 3 – 0 +265
Daniil Medvedev 3 – 1 +315
Daniil Medvedev 3 – 2 +450
Frances Tiafoe 3 – 0 +525
Frances Tiafoe 3 – 1 +475
Frances Tiafoe 3 – 2 +525
Daniil Medvedev vs Frances Tiafoe
Set Betting – Two Chances
Daniil Medvedev 3-0 or 3-1 +115
Daniil Medvedev 3-1 or 3-2 +130
Frances Tiafoe 3-0 or 3-1 +200
Frances Tiafoe 3-1 or 3-2 +185
Daniil Medvedev vs Frances Tiafoe
Set Spread
Daniil Medvedev -1.5 (+115)
Frances Tiafoe 1.5 (-150)
Daniil Medvedev vs Frances Tiafoe
Alternate Set Spread
Daniil Medvedev 1.5 (-335)
Frances Tiafoe -1.5 (+240)
Daniil Medvedev -2.5 (+315)
Frances Tiafoe 2.5 (-475)
Daniil Medvedev 2.5 (-1000)
Frances Tiafoe -2.5 (+550)
Daniil Medvedev vs Frances Tiafoe
Total Sets
Over 3.5 (-230)
Under 3.5 (+175)
Daniil Medvedev vs Frances Tiafoe
Alternate Total Sets
Over 4.5 (+200)
Under 4.5 (-275)
Daniil Medvedev vs Frances Tiafoe
Set Correct Score
Daniil Medvedev – 6 – 0 – S1 +7000
Daniil Medvedev – 6 – 1 – S1 +1700
Daniil Medvedev – 6 – 2 – S1 +1000
Daniil Medvedev – 6 – 3 – S1 +500
Daniil Medvedev – 6 – 4 – S1 +475
Daniil Medvedev – 7 – 5 – S1 +1400
Daniil Medvedev – 7 – 6 – S1 +625
Frances Tiafoe – 6 – 0 – S1 +10000
Frances Tiafoe – 6 – 1 – S1 +2800
Frances Tiafoe – 6 – 2 – S1 +1500
Frances Tiafoe – 6 – 3 – S1 +700
Frances Tiafoe – 6 – 4 – S1 +600
Frances Tiafoe – 7 – 5 – S1 +1700
Frances Tiafoe – 7 – 6 – S1 +725
Daniil Medvedev vs Frances Tiafoe
1st Set Correct Score – Any Player
6-0 +3300
6-1 +1100
6-2 +600
6-3 +275
6-4 +240
7-5 +750
7-6 +300
Daniil Medvedev vs Frances Tiafoe
1st Set Correct Score Groups
Daniil Medvedev 6-0, 6-1 or 6-2 +600
Daniil Medvedev 6-3 or 6-4 +225
Daniil Medvedev 7-5 or 7-6 +400
Frances Tiafoe 6-0, 6-1 or 6-2 +850
Frances Tiafoe 6-3 or 6-4 +300
Frances Tiafoe 7-5 or 7-6 +500
Daniil Medvedev vs Frances Tiafoe
2nd Set Correct Score Groups
Daniil Medvedev 6-0, 6-1 or 6-2 +600
Daniil Medvedev 6-3 or 6-4 +225
Daniil Medvedev 7-5 or 7-6 +400
Frances Tiafoe 6-0, 6-1 or 6-2 +850
Frances Tiafoe 6-3 or 6-4 +300
Frances Tiafoe 7-5 or 7-6 +500
Daniil Medvedev vs Frances Tiafoe
Set Exacta – Best of 5
Daniil Medvedev WWW +300
Daniil Medvedev LWWW +450
Daniil Medvedev WLWW +450
Daniil Medvedev WWLW +450
Daniil Medvedev LLWWW +2800
Daniil Medvedev LWLWW +2800
Daniil Medvedev LWWLW +2800
Daniil Medvedev WLLWW +2800
Daniil Medvedev WLWLW +2800
Daniil Medvedev WWLLW +2800
Frances Tiafoe WWW +475
Frances Tiafoe LWWW +550
Frances Tiafoe WLWW +550
Frances Tiafoe WWLW +550
Frances Tiafoe LLWWW +3000
Frances Tiafoe LWLWW +3000
Frances Tiafoe LWWLW +3000
Frances Tiafoe WLLWW +3000
Frances Tiafoe WLWLW +3000
Frances Tiafoe WWLLW +3000
Daniil Medvedev vs Frances Tiafoe
Tiebreak In Set
Yes – S1 +300
No – S1 -450
Daniil Medvedev vs Frances Tiafoe
To Lose 1st Set & Win The Match
Daniil Medvedev +450
Frances Tiafoe +550
Daniil Medvedev vs Frances Tiafoe
To Win 1st Set & Win The Match
Daniil Medvedev +120
Frances Tiafoe +200
Daniil Medvedev vs Frances Tiafoe
To Win & Both Players To Win A Set
Daniil Medvedev +140
Frances Tiafoe +200
Daniil Medvedev vs Frances Tiafoe
Will there be a tie-break in the match?
No -121
Daniil Medvedev vs Frances Tiafoe
Total Match Tie Breaks
Over 1.5 +325
Under 1.5 -500
Over 2.5 +1000
Daniil Medvedev vs Frances Tiafoe
Correct Score After 2 Games
Daniil Medvedev 2-0 +400
Frances Tiafoe 2-0 +500
Draw 1-1 -275
Daniil Medvedev vs Frances Tiafoe
Correct Score After 4 Games
Daniil Medvedev 4-0 +2000
Daniil Medvedev 3-1 +260
Frances Tiafoe 4-0 +2500
Frances Tiafoe 3-1 +325
Draw 2-2 -120
Daniil Medvedev vs Frances Tiafoe
Correct Score After 6 Games
Daniil Medvedev 6-0 +7000
Daniil Medvedev 5-1 +1000
Daniil Medvedev 4-2 +240
Frances Tiafoe 6-0 +9000
Frances Tiafoe 5-1 +1200
Frances Tiafoe 4-2 +300
Draw 3-3 +125
Daniil Medvedev vs Frances Tiafoe
Race To 2 Games
Daniil Medvedev -135
Frances Tiafoe +105
Daniil Medvedev vs Frances Tiafoe
Race To 3 Games
Daniil Medvedev -135
Frances Tiafoe +105
Daniil Medvedev vs Frances Tiafoe
Race To 4 Games
Daniil Medvedev -135
Frances Tiafoe +105
Daniil Medvedev vs Frances Tiafoe
Race To 5 Games
Daniil Medvedev -135
Frances Tiafoe +105
Daniil Medvedev vs Frances Tiafoe
Lead After 4 Games
Daniil Medvedev +240
Frances Tiafoe +300
Tie -120
Daniil Medvedev vs Frances Tiafoe
Lead After 6 Games
Daniil Medvedev +185
Frances Tiafoe +240
Tie +125
Daniil Medvedev vs Frances Tiafoe
Odd/Even Total Games
Even -110
Odd -110
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game
To Hold Serve -650
To Be Broken +400
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game Score
Hold to Love +375
Hold to 15 +250
Hold to 30 +300
Hold to 40 +350
Broken to Love +4000
Broken to 15 +1600
Broken to 30 +1000
Broken to 40 +1200
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game – Score After 2 Points
Daniil Medvedev 30-0 +120
15-15 EVEN
Frances Tiafoe 0-30 +600
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game – To Serve An Ace
Yes -185
No +140
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game – To Face Break Point
Yes +200
No -275
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game – To Deuce
Yes +275
No -400
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev – 1st Service Game – Total Points
4 Points +275
5 Points +210
6 Points +220
7+ Points +275
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game
To Hold Serve -500
To Be Broken +325
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game Score
Hold to Love +450
Hold to 15 +275
Hold to 30 +300
Hold to 40 +350
Broken to Love +3300
Broken to 15 +1400
Broken to 30 +900
Broken to 40 +1100
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game – Score After 2 Points
Frances Tiafoe 30-0 +125
15-15 EVEN
Daniil Medvedev 0-30 +550
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game – To Serve An Ace
Yes +240
No -335
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game – To Face Break Point
Yes +175
No -230
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game – To Deuce
Yes +250
No -350
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe – 1st Service Game – Total Points
4 Points +400
5 Points +220
6 Points +210
7+ Points +250
Daniil Medvedev vs Frances Tiafoe
Most Aces
Daniil Medvedev -5000
Frances Tiafoe +1800
Draw +2000
Daniil Medvedev vs Frances Tiafoe
Most Double Faults
Daniil Medvedev -300
Draw +950
Frances Tiafoe +300
Daniil Medvedev vs Frances Tiafoe
First Service Break
Daniil Medvedev -135
Frances Tiafoe +105
Daniil Medvedev vs Frances Tiafoe
Will Daniil Medvedev Win At Least One Set?
Yes -1000
No +550
Daniil Medvedev vs Frances Tiafoe
Will Frances Tiafoe Win At Least One Set?
Yes -400
No +275
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev To Win Two Sets
Yes -300
No +220
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe To Win Two Sets
Yes -175
No +135
Daniil Medvedev vs Frances Tiafoe
Daniil Medvedev To Win From Behind
Yes +350
No -550
Daniil Medvedev vs Frances Tiafoe
Frances Tiafoe To Win From Behind
Yes +450
No -750
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US Open ATP Tennis Predictions
Tennis Pick: Alternate Total Games –
Under 38.5 (EVEN)
A $100 Bet on that Props will return $200
Tennis Odds & Props source: Bovada Sportsbook
