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Kyler Murray’s Cardinals Face Tough Test Against 49ers

The division rival San Francisco 49ers and Arizona Cardinals will meet on the field on Sunday at State Farm Stadium.

(Photo by Getty Images) Kyler Murray

San Francisco at Arizona

When: 4:05 PM ET, Sunday, December 17, 2023
Where: State Farm Stadium, Glendale, Arizona
Where to watch: CBS

Game Odds, Spread, Moneyline & Total

San Francisco 49ers @ Arizona Cardinals
Moneyline

San Francisco 49ers   -900
Arizona Cardinals   +575

San Francisco 49ers @ Arizona Cardinals
Point Spread

San Francisco 49ers   -12.0 (-110)
Arizona Cardinals   12.0 (-110)

San Francisco 49ers @ Arizona Cardinals
Total

Over   48.5 (-110)
Under   48.5 (-110)

Team Record & Betting Stats

Name Record ATS Offense Defense
San Francisco 10-3 7-6 29.23 15.77
Arizona 3-10 7-6 17.69 25.46
Name ATS Home ATS Away OU Record
San Francisco 3-3 4-3 6-6-1
Arizona 4-2 3-4 7-6

San Francisco 49ers Last 5 Games

Opponent score Result line ATS Result
SEA 28-16 W -14.5/44.5 L/U
PHI 42-19 W -3/47 W/O
SEA 31-13 W -7/43 W/O
TB 27-14 W -13.5/42 L/U
JAC 34-3 W -3/44.5 W/U

Arizona Cardinals Last 5 Games

Opponent score Result line ATS Result
PIT 24-10 W 6/41 W/U
LAR 14-37 L 3/45 L/O
HOU 16-21 L 5.5/48 W/U
ATL 25-23 W 2/43.5 W/O
CLE 0-27 L 13/38 L/U

Game Preview

It’s homecoming weekend for Brock Purdy as his San Francisco 49ers continue the chase for the No. 1 NFC seed on Sunday against the Arizona Cardinals in Glendale, Ariz.

The 49ers (10-3) are the first team to clinch a playoff spot. They also are on a five-game winning streak during which they have outscored opponents 162-65.

The Cardinals (3-10) are rested after a bye week, have won two of their last four games since Kyler Murray’s return, and are looking to spoil the Purdy party.

by FLM

Betting Odds Trends

San Francisco 49ers
San Francisco is 16-8 ATS in its last 24 games
San Francisco is 5-0 SU in its last 5 games
San Francisco is 9-3 SU in its last 12 games on the road
San Francisco is 4-2 ATS in its last 6 games when playing Arizona
San Francisco is 4-7-1 ATS in its last 12 games when playing Arizona
San Francisco is 4-2 SU in its last 6 games when playing Arizona
The total has gone OVER in 4 of San Francisco’s last 5 games when playing Arizona
San Francisco is 3-6 SU in its last 9 games when playing on the road against Arizona
The total has gone UNDER in 5 of San Francisco’s last 7 games when playing on the road against Arizona
Arizona Cardinals
Arizona is 4-2 ATS in its last 6 games
Arizona is 3-17 SU in its last 20 games
Arizona is 5-2 ATS in its last 7 games at home
Arizona is 3-17 SU in its last 20 games at home
The total has gone OVER in 5 of Arizona’s last 5 games at home
Arizona is 2-4 ATS in its last 6 games when playing San Francisco
Arizona is 2-4 SU in its last 6 games when playing San Francisco
The total has gone OVER in 4 of Arizona’s last 5 games when playing San Francisco
Arizona is 6-3 SU in its last 9 games when playing at home against San Francisco
The total has gone UNDER in 5 of Arizona’s last 7 games when playing at home against San Francisco

San Francisco Injuries

Player Status/Updated
Darrell Luter Jr. Prob Sun – Hamstring – 12/15/23
Aaron Banks Ques Sun – Hip – 12/15/23
Dre Greenlaw Ques Sun – Ankle – 12/15/23
Charvarius Ward Ques Sun – Groin – 12/13/23
Spencer Burford Ques Sun – Knee – 12/12/23
Oren Burks Out Sun – Knee – 12/15/23
Javon Hargrave Out Sun – Hamstring – 12/15/23
Ross Dwelley Out Sun – Ankle – 12/15/23
Elijah Mitchell Out Sun – Knee – 12/15/23
Arik Armstead Out Sun – Foot – 12/15/23
Ray-Ray McCloud III Out indefinitely – Ribs – 12/9/23
George Odum I-R – Bicep – 11/27/23
Talanoa Hufanga I-R – Knee – 11/21/23
Nick Zakelj I-R – Bicep – 11/15/23
Drake Jackson Out indefinitely – Knee – 11/11/23
Cameron Latu I-R – Knee – 8/29/23
Danny Gray Out indefinitely – Shoulder – 8/30/23

Arizona Injuries

Player Status/Updated
Kyler Murray Prob Sun – Thumb – 12/15/23
Kevin Strong Prob Sun – Knee – 12/15/23
Jalen Thompson Prob Sun – Toe – 12/15/23
Emari Demercado Prob Sun – Neck – 12/15/23
Starling Thomas V Prob Sun – Ankle – 12/15/23
Antonio Hamilton Sr. Prob Sun – Groin – 12/15/23
Elijah Wilkinson Prob Sun – Neck – 12/16/23
Krys Barnes Ques Sun – Ribs – 12/15/23
Blake Gillikin Ques Sun – Back – 12/15/23
Geoff Swaim Ques Sun – Back – 12/15/23
Zach Pascal Ques Sun – Personal – 12/12/23
Marquise Brown Ques Sun – Heel – 12/12/23
Michael Wilson Ques Sun – Shoulder – 12/12/23
Tyreke Smith Out Sun – Personal – 12/15/23
Kyzir White I-R – Bicep – 11/21/23
Leki Fotu Out indefinitely – Hand – 11/21/23
Bobby Price Out Sun – Undisclosed – 12/15/23
Carlos Watkins Out indefinitely – Bicep – 9/20/23
L.J. Collier Out indefinitely – Bicep – 9/16/23
Jon Gaines II I-R – Knee – 8/29/23
Pat Elflein I-R – Undisclosed – 8/28/23
Rashad Fenton I-R – Undisclosed – 8/14/23
Marlon Mack I-R – Achilles – 8/10/23
Matt Hembrough I-R – Back – 7/25/23

NFL Parlay Picks & Free Predictions

Final Score: San Francisco 30-22
The Pick: Arizona +12 & Over 48½
A $100 Parlay Bet will return $364 in total Payout

NFL Odds source: Bovada Sportsbook

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