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LA Dodgers (73-55) at San Diego (72-56)
- When: Aug 22 2025, 9:40 PM
- Where: PETCO Park, San Diego
- Where to watch: SDPA
Dodgers vs Padres – Game Preview, Prediction and Player Props
Moneyline: LA Dodgers -120
Total: 8.0
RunLine: LA Dodgers -1.5 (+135)
Los Angeles Dodgers Betting Outlook
The Dodgers roll into San Diego as slight -120 moneyline favorites, with the total set at 8.0 runs. Despite some recent inconsistency in Colorado, Los Angeles still sits atop the NL West and has already locked up the season series against San Diego, winning eight of ten matchups. That head-to-head dominance provides a built-in tiebreaker should things get tight in the standings.
Blake Snell (3-1, 1.80 ERA) takes the ball against his former team. The reigning NL Cy Young winner has been lights out when facing San Diego, allowing just one earned run across two starts this season. If he can replicate last weekend’s six-inning shutout performance, the Dodgers’ strong lineup should have enough cushion to grab another win.
Dodgers Prop Pick: Freddie Freeman Over 1.5 Total Bases — Freeman has been crushing right-handed pitching, and Darvish’s recent struggles make this matchup favorable.
San Diego Padres Betting Outlook
The Padres enter this series in familiar territory, riding momentum after three straight wins over the Giants. The problem? The last time they came in hot, the Dodgers promptly swept them. This weekend is their last chance to flip that script in the regular season.
Yu Darvish (2-3, 5.97 ERA) will try to steady things on the mound. While he struggled last week against the Dodgers, history says he can be tough on them, boasting a 2.55 ERA in 16 career regular-season starts versus L.A. If San Diego’s offense can replicate the firepower it showed in outscoring San Francisco 21-6 across three games, they’ll have a fighting chance to even the division race.
Padres Prop Pick: Fernando Tatis Jr. to Record a Run — with the way he’s been setting the table lately, if San Diego scores, chances are Tatis is crossing the plate.
Prediction
The Dodgers’ pitching advantage with Snell facing his old team is hard to ignore, especially given L.A.’s season-long edge in this rivalry. San Diego’s bats should keep it competitive, but the Dodgers’ track record speaks loudly here.
Final Score Prediction: Dodgers 5, Padres 4
Lean: LA Dodgers (-120)
Total: Over 8.0 (-105)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
