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Tigers vs Red Sox Odds, Prediction & Final Game Preview

Betting preview for Tigers vs Red Sox with odds, spread, total and score prediction in Sunday’s finale.

(Photo by Getty Images) Chris Paddack
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Detroit (87-74) at Boston (88-73)

  • When: Sep 28 2025, 3:05 PM
  • Where: Fenway Park, Boston
  • Where to watch: NESN

Tigers vs. Red Sox – Game Betting Preview & Prediction

Moneyline: Detroit -132 
Spread: Detroit -1.5 (+137)
Total: 9.0

Detroit Tigers Betting Outlook

The Detroit Tigers sealed back-to-back playoff trips for the first time since 2014 with Saturday’s 2-1 win in Boston. After snapping an eight-game skid, they’ve now won two of their last three and remain tied atop the AL Central with Cleveland, though the Guardians own the tiebreaker.

Jahmai Jones’ clutch two-run single Saturday was the difference, and he’s been red-hot at the plate, going 7-for-15 in his last six games. Now, Detroit pivots to preparing for October. Tarik Skubal, the Cy Young frontrunner, is being saved for the postseason, leaving Chris Paddack (5-11, 5.27 ERA) to take the mound in the finale.

Paddack has struggled historically against Boston (1-1, 6.07 ERA in three starts) but is tasked with eating innings here while the Tigers keep their eyes firmly on the bigger prize. With their playoff spot secured, the motivation is still high, they’d love to carry momentum into the Wild Card round.

Boston Red Sox Betting Outlook

Boston already locked up its first postseason appearance since 2021 with Friday’s dramatic walk-off win but fell flat on Saturday after resting several regulars. The Red Sox are just 6-11 in their last 17 home games, though they’ve been solid on the road at 14-6.

Even in a subdued lineup, Ceddanne Rafaela continues to shine, delivering hits in seven of his last eight games and serving as the Friday hero with a walk-off triple. Manager Alex Cora acknowledged his team might have been “hung over” from celebrating Friday, but the bigger picture is clear: Boston weathered injuries and roster shuffling all year and still met expectations.

The pitching plan for Sunday remains unsettled, as Boston may treat the game like a bullpen day, focusing more on postseason readiness than pushing starters deep into innings.

Betting Outlook & Prediction

With Skubal resting, this is less about Detroit’s best arms and more about staying sharp. Paddack isn’t dominant, but Detroit’s lineup looks a touch more locked in right now compared to Boston’s post-clinch approach. Expect a competitive, higher-scoring game with the Tigers edging it late.

Score Prediction: Tigers 6, Red Sox 4
Pick: Detroit (-132)
Total: Over 9.0 (-112) 

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