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White Sox vs Yankees Expert MLB Picks

Gerrit Cole leads Yankees into key series opener against Chicago.

(Photo by Getty Images) Gerrit Cole
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Chi. White Sox (38-32) at NY Yankees (43-27)

  • When: Jun 16 2026, 7:05 PM
  • Where: Yankee Stadium, Bronx
  • TV: YES

Chi. White Sox vs NY Yankees MLB Preview & Pick

Moneyline: NY Yankees -145 
Runline: NY Yankees -1.5 (+151)
Total: 7.5

Chicago White Sox Betting Preview

The White Sox are no longer playing like a cute underdog story. They arrive in New York after going 5-3 against the Phillies, Braves, and Dodgers, part of an 11-5 surge that has pushed them over .500.

Chicago’s offense has shown real fight, including a six-run sixth inning against the Dodgers powered by home runs from Sam Antonacci, Colson Montgomery, and Chase Meidroth. Montgomery has cooled off, hitting just .147 over his last nine games, but Miguel Vargas is batting .318 across his last 11, while Meidroth is hitting .333 over that same span.

Davis Martin gets the ball at 9-2 with a 2.41 ERA. He has three scoreless starts this season, has not allowed a homer in four straight outings, and owns serious prop value if he keeps the ball in the park.

White Sox Player Prop Pick: Davis Martin Under 2.5 Earned Runs – Martin’s form is strong enough to keep Chicago competitive, especially with the total sitting low at 7.5.

New York Yankees Betting Preview

The Yankees enter as -145 moneyline favorites, with the run line at -1.5 (+151). Even without Aaron Judge, New York keeps finding ways to win, going 7-4 since losing him to a fractured right rib.

Paul Goldschmidt delivered a huge late homer against Toronto, while Ben Rice and Jose Caballero powered a five-run ninth in another comeback win. This lineup is missing its biggest bat, but the situational hitting has been sharp.

Gerrit Cole starts for New York at 1-1 with a 2.45 ERA. His last outing lasted only four innings, but his command and big-game profile still give the Yankees the edge at home.

Yankees Player Prop Pick: Gerrit Cole Over 5.5 StrikeoutsCole should attack a White Sox lineup that can be streaky, and his swing-and-miss upside remains the best prop angle.

MLB Expert Picks & Final Score Prediction

This matchup feels tighter than the price suggests because Martin has been excellent, but Yankee Stadium and Cole tilt the edge toward New York.

Final Score: Yankees 4, White Sox 3
Lean:  NY Yankees ML (-145)
Total: 
Under 7.5 (-102) 

U.S. Open 2026 Odds

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