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Reds vs Cubs MLB Baseball Odds & Parlay Picks

The division rival Cincinnati and Chi. Cubs are set to renew hostilities when they meet at Wrigley Field.

(Photo by Getty Images) Andrew Abbott

Cincinnati (28-29) at Chi. Cubs (35-21)

  • When: May 30 2025, 2:20 PM
  • Where: Wrigley Field, Chicago
  • Where to watch: MLB Network

Reds vs. Cubs – Game Betting Preview & Prediction

Moneyline: Chi Cubs -160 | Total: 8.5

Chicago Cubs Outlook: Crow-Armstrong Catching Fire

The Chicago Cubs are rolling into the weekend riding a four-game win streak, and the energy at Wrigley is electric. Leading the charge? None other than Pete Crow-Armstrong. The young outfielder has been on a tear, smacking his 15th home run and swiping his 16th bag this week and we’re not even halfway through the season. That kind of power-speed combo this early is elite territory, no matter how he downplays it.

Chicago’s bats were hot during their recent series against the Reds, where they racked up 28 runs. Though they cooled slightly against the Rockies, they still managed a sweep. Colin Rea gets the nod again for Friday’s opener, looking to redeem himself after allowing six runs in his last outing against Cincy.

Rea may have a solid 5-1 record versus the Reds lifetime, but his 5.88 ERA in those games is worth noting if you’re betting the total. Expect some early offense if his control isn’t sharp.

Cincinnati Reds Outlook: Abbott Shining Bright

The Reds limp into this series with some uncertainty surrounding Austin Hays, who left Wednesday’s game with a sore foot. That’s a blow to a lineup that needs his .303 average and steady power presence. But there’s a silver lining: Andrew Abbott is on the bump.

Abbott has been lights out this month, posting a ridiculous 0.70 ERA in five May starts. He kept the Cubs in check last Saturday with 5 2/3 strong innings and could be in contention for NL Pitcher of the Month with another gem here. The only Cub who’s had his number? Dansby Swanson, who’s peppered him with two doubles and a homer in just 11 plate appearances.

The Reds will need Abbott to carry them early and hope their bullpen doesn’t spoil the party late.

Final Score Prediction

Even with Abbott dealing, the Cubs’ overall momentum, deeper lineup, and home-field edge make them the better side here. Chicago pulls it out 5–3 in a gritty, high-leverage game.

Score Prediction: Cubs 5, Reds 3
Side: Chi. Cubs RL -1.5 (+130)
Best Bet: Under 8.5 (-110)

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